PMID: 7581340Sep 1, 1995Paper

The primary structure of an Entamoeba histolytica beta-hexosaminidase A subunit

The Journal of Eukaryotic Microbiology
M J Beanan, G B Bailey

Abstract

An Entamoeba histolytica gene (hex-A1) that encodes subunit A of the lysosomal enzyme beta-hexosaminidase has been cloned and sequenced. The inferred 59 kDa hex-A1 protein has the same molecular weight and 32% amino acid residue identity with the human and mouse proteins and 28% residue identity with the Dictyostelium protein. Northern blot analysis identified a mRNA of approximately 1.6 kb, which is in agreement with the expected size of a mRNA encoding the 522 amino acid hex-A1 protein. Southern blot analysis indicated the presence of at least two beta-hexosaminidase A subunit genes.

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Citations

Feb 7, 2001·Clinical Microbiology Reviews·M Espinosa-Cantellano, A Martínez-Palomo
Apr 30, 1998·The Journal of Eukaryotic Microbiology·W M Spice, J P Ackers
Jan 24, 2006·Protein Expression and Purification·Jared J AumillerDonald L Jarvis
Aug 15, 2019·Biological Reviews of the Cambridge Philosophical Society·Harry C TjondroMorten Thaysen-Andersen
Apr 16, 1998·Pharmacology & Therapeutics·M HorschD M Rast

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