The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance.

Cell Metabolism
Robert V FareseTobias C Walther

Abstract

Excessive deposition of fat in the liver (hepatic steatosis) is frequently accompanied by hepatic insulin resistance. Whether this correlation is due to a causal relationship between the conditions has been the subject of considerable debate, and the literature abounds with conflicting data and theories. Here we provide a perspective by defining the problem and its challenges, analyzing the possible causative relationships, and drawing some conclusions.

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Sep 21, 2013·Diabetologia·Francesco OrienteFrancesco Beguinot
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