The prognosis of gestational trophoblastic neoplasia patient with residual lung tumor after completing treatment

Gynecologic Oncology
Junjun YangXiuyu Yang

Abstract

To analyze retrospectively the prognosis of gestational trophoblastic neoplasia (GTN) patients who achieved normal beta-hCG titer after completing treatment but remained with residual lung tumor. A total of 1,130 GTN patients were hospitalized at Peking Union Medical College Hospital from January 1985 to January 2004. Among these patients, 901 achieved complete remission (CR); 152 achieved normal blood beta-hCG titer after the completion of treatment but remained with residual lung tumor (defined as partial remission). Retrospective analyses were carried out on the 152 patients. Statistical analysis was used to compare the recurrent rate of the CR patients with the progression rate of the 152 patients. 17 of the 152 patients lost follow-up. Of the rest 135 patients followed up from 14 to 110 months, 83 showed no significant changes as to their residual tumors; 46 patients' residual tumors diminished or disappeared; and the other 6 patients got progression of disease (PD), with beta-hCG level going up 6-8 months after completing treatment. There is no significant statistical difference (P > 0.05) between the recurrent rate of the 901 CR patients and the progression rate of the 152 patients. There is also no significant statistic...Continue Reading

References

Mar 27, 2003·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·M MoodleyJ Moodley
Nov 15, 2003·Best Practice & Research. Clinical Obstetrics & Gynaecology·John T Soper
Jul 21, 2004·Gynecologic Oncology·Fatemeh GhaemmaghamiParviz Hanjani

❮ Previous
Next ❯

Citations

Jan 15, 2013·European Journal of Nuclear Medicine and Molecular Imaging·P MapelliM Candiani
Aug 4, 2009·Placenta·J ZhaoX Y Yang
Apr 1, 2009·Seminars in Oncology·Neil S HorowitzRoss S Berkowitz
Sep 1, 2007·Current Opinion in Oncology·Sarah Ngan, Michael J Seckl
Jun 11, 2009·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Yang CaoXiuyu Yang
Oct 21, 2010·Expert Opinion on Pharmacotherapy·Noah RodriguezRoss S Berkowitz
Aug 25, 2018·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Xi LiKezhen Li
Jun 9, 2020·Journal of Family Medicine and Primary Care·Seyedeh Reyhaneh Yousefi Sharami, Elham Saffarieh
Nov 18, 2017·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·A SantaballaE García-Martinez
Jun 18, 2020·Cancer Management and Research·Luo ZhaoHongsheng Liu
Jan 9, 2010·Fetal and Pediatric Pathology·N J Sebire, Iain Lindsay
Feb 25, 2021·Best Practice & Research. Clinical Obstetrics & Gynaecology·Antonio BragaRoss S Berkowitz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Australian & New Zealand Journal of Obstetrics & Gynaecology
G B Duff
European Journal of Obstetrics, Gynecology, and Reproductive Biology
L-C HornJ Einenkel
Best Practice & Research. Clinical Obstetrics & Gynaecology
Elizabeth I O GarnerLari Wenzel
© 2022 Meta ULC. All rights reserved