The prognostic significance of clinical and pathological features in hepatocellular carcinoma

World Journal of Gastroenterology : WJG
Lun-Xiu Qin, Zhao-You Tang

Abstract

The prognosis of patients with HCC still remains dismal. The life expectancy of HCC patients is hard to predict because of the high possibility of postoperative recurrence. Many factors, such as patient's general conditions, macroscopic tumor morphology, as well as tumor histopathology features, have been proven of prognostic significance. Female HCC patient often has a better prognosis than male patient, which might be due to the receptor of sex hormones. Younger patients often have tumors with higher invasiveness and metastatic potentials, and their survival and prognosis are worse than the older ones. Co-existing hepatitis status and hepatic functional reserve have been confirmed as risk factors for recurrence. Serum alpha-fetoprotein (AFP) is useful not only for diagnosis, but also as a prognostic indicator for HCC patients. AFP mRNA has been proposed as a predictive marker of HCC cells disseminated into the circulation and for metastatic recurrence. Many pathologic features, such as tumor size, number, capsule state, cell differentiation, venous invasion, intrahepatic spreading, and advanced pTNM stage, are the best-established risk factors for recurrence and important aspects affecting the prognosis of patients with HCC. ...Continue Reading

References

Apr 1, 1997·American Journal of Surgery·T NonamiH Takagi
Aug 1, 1997·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·T TanakaE Okamoto
Feb 14, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Y WadaM Kojiro
Aug 11, 1998·The European Journal of Surgery = Acta Chirurgica·K J PaquetW Ruppert
Dec 3, 1999·The British Journal of Surgery·C C WuF K P'eng
Dec 22, 1999·The British Journal of Surgery·S TakanoS Iwai
Feb 9, 2000·Japanese Journal of Cancer Research : Gann·J MuraseH Kinoshita
Mar 1, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·R T PoonJ Wong
Mar 7, 2000·Journal of the American College of Surgeons·T UtsunomiyaK Sugimachi
May 5, 2000·The Cochrane Database of Systematic Reviews·E S ChanK Soo
Aug 1, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·E VillaF Manenti
Oct 13, 2000·Journal of the American College of Surgeons·K HanazakiJ Amano
Dec 2, 2000·Journal of Gastroenterology and Hepatology·Z Y Tang
Dec 29, 2000·Journal of Clinical Gastroenterology·P TangkijvanichY Poovorawan
Dec 29, 2000·Journal of the American College of Surgeons·T OhkuboT Kosuge
Jan 12, 2001·Journal of Clinical Gastroenterology·T YoshidaM Monden
Jun 19, 2001·Hepatology Research : the Official Journal of the Japan Society of Hepatology·T SuouH Kawasaki
Oct 2, 2001·CA: a Cancer Journal for Clinicians·R T GreenleeM Thun

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Citations

Jun 5, 2002·World Journal of Gastroenterology : WJG·Lian-Xin LiuDa-Xun Piao
Apr 30, 2003·World Journal of Gastroenterology : WJG·Shao-Shan WangQing-Hui Qi
Apr 8, 2003·World Journal of Gastroenterology : WJG·Run-Zhou NiXian-Yong Meng
Jul 11, 2003·World Journal of Gastroenterology : WJG·Jun-Fei JinWei Xie
Sep 13, 2003·World Journal of Gastroenterology : WJG·Jun QianThomas Vogl
Feb 5, 2004·World Journal of Gastroenterology : WJG·Wen-Hua Xiao, Wei-Wen Liu
Mar 16, 2004·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Jilin Yi, Geng Tian
Aug 17, 2004·The American Journal of Gastroenterology·Kuo-Shyang JengYi-Chun Tsai
Jun 11, 2005·Journal of Gastroenterology and Hepatology·William KempStuart K Roberts
Jun 7, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Yu-Chen HsuShiaw-Der Yang
Jun 29, 2006·World Journal of Gastroenterology : WJG·Ning RenZhao-You Tang
May 5, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Ming-Chin YuMiin-Fu Chen
May 12, 2011·Pathology Research International·Zenta Walther, Dhanpat Jain
Oct 28, 2011·Pathology International·Myeong Jun SongSeung Kew Yoon
Jun 20, 2013·The Journal of International Medical Research·Zimin LiuJun Liang
Apr 28, 2018·Journal of Biomaterials Applications·Lei XuXiaoqiu Zhou
Aug 14, 2002·World Journal of Gastroenterology : WJG·Hong-Chi JiangLin-Feng Wu
Aug 14, 2002·World Journal of Gastroenterology : WJG·Lian-Xin LiuMin Wu
Jul 9, 2004·World Journal of Gastroenterology : WJG·Sui-Hai SiPing Zhou
Mar 31, 2004·World Journal of Gastroenterology : WJG·Dong XuPei-Hui Song
Jun 5, 2002·World Journal of Gastroenterology : WJG·Lun-Xiu Qin, Zhao-You Tang
Oct 17, 2003·World Journal of Gastroenterology : WJG·Zhen-Yu YinJie-Shou Li
Aug 15, 2003·World Journal of Gastroenterology : WJG·Dao-Yong LiuChong-Zhi Zhou
Dec 16, 2006·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Mei-Sze ChuaSamuel So
Mar 19, 2009·Journal of Cancer Research and Clinical Oncology·Xin-Da ZhouShuang-Jian Qiu
Jun 1, 2008·Hepatology International·Shu-Min ZhangBo-Heng Zhang
Nov 6, 2015·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Dai Hoon HanJin Sub Choi
Dec 1, 2017·Annals of Surgical Treatment and Research·Dong Do YouYong Gyu Park

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