The prognostic value of health-related quality of life in patients with Chagas heart disease

Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation
Henrique S CostaManoel Otávio da Costa Rocha

Abstract

To verify the prognostic value of health-related quality of life (HRQoL) and the differences in HRQoL and clinical variables between groups of Chagas heart disease (CHD) patients with and without cardiovascular adverse events. Seventy-five CHD patients were evaluated by echocardiography, maximal exercise testing, and Short-form of Health Survey (SF-36) Questionnaire. Patients were followed during 6 years. In the statistical analysis, uni- and multivariate Cox regression were performed to verify the accuracy of the HRQoL in predicting cardiovascular events. After the follow-up period (41 ± 12 months), 20 patients (27%) had adverse events. Those with poor outcome had lower left ventricular ejection fraction (LVEF) (p = 0.002), higher left ventricular end-diastolic diameter (LVDd) (p = 0.019), and worse scores in general health perceptions (p = 0.047), social role functioning (p = 0.026), and mental component summary (p = 0.043) of SF-36. Patients with lower LVEF (p = 0.003), higher LVDd (p = 0.022), worse HRQoL in the general heath perceptions domain (p = 0.022), and mental component summary (p = 0.031) were associated with worse prognosis. In the multivariate Cox regression, LVEF (HR 0.94, 95% CI from 0.90 to 0.98, p = 0.007) an...Continue Reading

References

Oct 28, 1999·The New England Journal of Medicine·C R ColeM S Lauer
Feb 21, 2006·Journal of the American College of Cardiology·Paul A HeidenreichUNKNOWN Cardiovascular Outcomes Research Consortium
Aug 7, 2007·Expert Review of Anti-infective Therapy·Manoel O C RochaAntonio L Ribeiro
Sep 11, 2007·Journal of Cardiac Failure·Mark D SullivanJohn A Spertus
Dec 5, 2008·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Olatz GarinJordi Alonso
Aug 10, 2010·Heart & Lung : the Journal of Critical Care·Viviane Martinelli PelegrinoMarcus Vinícius Simões
Nov 4, 2010·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Yaeko OzakiEros Antonio de Almeida
May 3, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Naoko KatoRyozo Nagai
Jul 27, 2011·Arquivos brasileiros de cardiologia·Jadelson Pinheiro de AndradeJoão Carlos Pinto Dias
Aug 1, 2012·Nature Reviews. Cardiology·Antonio L RibeiroManoel O C Rocha
Aug 28, 2012·European Journal of Heart Failure·Josep LupónAntoni Bayes-Genis
Oct 27, 2012·Expert Review of Cardiovascular Therapy·Maria Carmo Pereira NunesAntonio Luiz Ribeiro
Jun 19, 2013·Journal of the American College of Cardiology·Maria Carmo Pereira NunesUNKNOWN Council on Chagas Disease of the Interamerican Society of Cardiology
Nov 10, 2013·PLoS Neglected Tropical Diseases·Peter J HotezBernard Pecoul
Jan 7, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Roberto M LangJens-Uwe Voigt
Feb 14, 2015·PLoS Neglected Tropical Diseases·Ana Requena-MéndezJose Muñoz
Feb 26, 2015·European Child & Adolescent Psychiatry·A MasilloP Fiori Nastro
Sep 4, 2015·Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery·Bożena Szyguła-JurkiewiczLech Poloński
May 16, 2017·European Journal of Internal Medicine·Spinello AntinoriMario Corbellino

❮ Previous
Next ❯

Citations

Jul 9, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Henrique Silveira CostaManoel Otávio da Costa Rocha
Nov 12, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Whesley Tanor SilvaManoel Otávio da Costa Rocha
Apr 18, 2021·Tropical Medicine & International Health : TM & IH·Matheus Ribeiro ÁvilaHenrique Silveira Costa
Jun 24, 2021·Revista Do Instituto De Medicina Tropical De São Paulo·Nayara Ragi BaldoniClareci Silva Cardoso
Oct 31, 2021·ESC Heart Failure·Sindhu ChadalawadaAndrés F Henao-Martínez

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology
Peter JohanssonUrban Alehagen
Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
Quan LiFang Chen
Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Xiaoning WuYumin Luo
© 2022 Meta ULC. All rights reserved