The prognostic value of positive T-wave in lead aVR in hemodialysis patients

Clinical and Experimental Nephrology
Andrzej JaroszyńskiTodd T Schlegel

Abstract

Given that cardiac disease is the leading cause of mortality in hemodialysis (HD) patients, identification of patients at risk for cardiac mortality is crucial. The aim of this study was to determine if positive T-wave amplitude in lead aVR (TaVR) was predictive of cardiovascular (CV) mortality and sudden cardiac death (SCD) in a group of HD patients. After exclusion, 223 HD patients were prospectively followed-up for 25.43 ± 3.56 months. Patients were divided into TaVR negative (n = 186) and TaVR positive (n = 37) groups. Myocardial infarction, diabetes and beta-blocker therapy were more frequent in positive TaVR patients. Patients with upright TaVR were older, had higher left ventricular mass index, lower ejection fraction, higher calcium × phosphate product, higher troponin T level, higher prevalence of ST-T abnormalities, and increased width of QRS complex and QT interval, compared with patients with negative TaVR. A Kaplan-Meier analysis showed that the cumulative incidences of CV mortality as well as SCD were higher in patients with positive TaVR compared with those with negative TaVR (log-rank, p < 0.001 in both cases). A multivariate analysis selected age [hazard ratio (HR) 1.71, p < 0.001], heart rate (HR 1.42, p = 0.0...Continue Reading

References

Jun 1, 1996·American Heart Journal·S AbeG Sloman
Sep 17, 1998·The New England Journal of Medicine·C A HerzogA J Collins
Mar 8, 2000·Current Problems in Cardiology·E A AshleyV F Froelicher
May 20, 2004·Kidney International·Alfred K CheungUNKNOWN HEMO Study Group
Dec 22, 2004·Kidney International·Graham A StewartAlan G Jardine
May 3, 2005·American Heart Journal·Kelly RichardsonVictor F Froelicher
Apr 23, 2008·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Swee Y TanVictor F Froelicher
Nov 4, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Andrzej JaroszynskiAndrzej Ksiazek
Jul 9, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Nicola KumarDavid Taube
Jul 19, 2011·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Kentarou OkudaYukio Ozaki
Aug 23, 2011·European Heart Journal·Cheuk-Kit WongUNKNOWN HERO-2 Investigators
Sep 13, 2011·The American Journal of Cardiology·Ismo AnttilaMika Kähönen
Jul 13, 2012·Circulation Journal : Official Journal of the Japanese Circulation Society·Kazuhiro DanHiroshi Ito
Jan 26, 2013·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Erkan AyhanMehmet Eren
Nov 22, 2013·Journal of Cardiovascular Electrophysiology·Dimitrios PoulikakosMarek Malik

❮ Previous
Next ❯

Citations

Dec 3, 2015·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Derek PhanSumeet S Chugh
Jul 29, 2016·Heart and Vessels·Yoshihiro TanakaKenshi Hayashi
Apr 26, 2017·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Yoshihiro TanakaKenshi Hayashi
Dec 19, 2018·BMC Nephrology·Andrzej JaroszyńskiWojciech Dąbrowski
Mar 16, 2017·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Yuji SatoShouichi Fujimoto

❮ Previous
Next ❯

Software Mentioned

Statistica

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiovascular Disorder in Diabetes

Diabetes is associated with an increased risk of cardiovascular disorders and heart failure. Discover the latest research here.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.