The Progress of Mitophagy and Related Pathogenic Mechanisms of the Neurodegenerative Diseases and Tumor

Neuroscience Journal
Ying SongKong-Jun Lu

Abstract

Mitochondrion, an organelle with two layers of membrane, is extremely vital to eukaryotic cell. Its major functions are energy center and apoptosis censor inside cell. The intactness of mitochondrial membrane is important to maintain its structure and function. Mitophagy is one kind of autophagy. In recent years, studies of mitochondria have shown that mitophagy is regulated by various factors and is an important regulation mechanism for organisms to maintain their normal state. In addition, abnormal mitophagy is closely related to several neurodegenerative diseases and tumor. However, the related signal pathway and its regulation mechanism still remain unclear. As a result, summarizing the progress of mitophagy and its related pathogenic mechanism not only helps to reveal the complicated molecular mechanism, but also helps to find a new target to treat the related diseases.

References

Jul 13, 2004·The Journal of Biological Chemistry·Ingrid KissováNadine Camougrand
Feb 29, 2008·Nature·Noboru MizushimaDaniel J Klionsky
Dec 17, 2009·EMBO Reports·Ivana NovakIvan Dikic
Jan 9, 2010·Current Opinion in Cell Biology·Sandra Turcotte, Amato J Giaccia
Jan 9, 2010·Cell Death and Differentiation·S MichiorriG Casari
Jan 26, 2010·Nature Cell Biology·Sven GeislerWolfdieter Springer
Mar 13, 2010·The Journal of Pathology·Danielle GlickKay F Macleod
Aug 24, 2010·Trends in Biochemical Sciences·Ruth Scherz-Shouval, Zvulun Elazar
Dec 18, 2010·Nature Chemical Biology·Angeleen FlemingDavid C Rubinsztein
Dec 24, 2010·Nature Reviews. Molecular Cell Biology·Richard J Youle, Derek P Narendra
Feb 8, 2011·Neurobiology of Disease·Ralph A Nixon, Dun-Sheng Yang
Mar 18, 2011·The New England Journal of Medicine·Francis X McCormackUNKNOWN MILES Trial Group
Mar 25, 2011·Biochemical Society Transactions·Ivana Bjedov, Linda Partridge
Mar 29, 2011·Pharmacology & Therapeutics·Jean M Mulcahy Levy, Andrew Thorburn
May 24, 2011·Journal of Neurochemistry·Zelda H Cheung, Nancy Y Ip
Jul 2, 2011·Current Pharmaceutical Design·Robert Taylor, Scott J Goldman
Nov 19, 2011·The Journal of Immunology : Official Journal of the American Association of Immunologists·Masashi KitazawaFrank M LaFerla
Dec 23, 2011·The Biochemical Journal·Jisun LeeJianhua Zhang
Jun 13, 2012·Brain : a Journal of Neurology·Véronique SchaefferMichel Goedert
Jul 12, 2012·Nature Biotechnology·Heesun CheongCraig B Thompson
Aug 15, 2012·Immunological Reviews·Katelin N TownsendJulian J Lum
Sep 5, 2012·Biological Chemistry·Wen-Xing Ding, Xiao-Ming Yin
Jul 25, 2013·Frontiers in Neurology·Karl GrenierEdward A Fon
Aug 8, 2013·Nature Medicine·Ralph A Nixon
Aug 14, 2013·Autophagy·Kim Wager, Claire Russell
Jul 30, 2014·Cell Reports·Paolo E PorporatoPierre Sonveaux

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Citations

Apr 14, 2017·Cellular and Molecular Neurobiology·Mengqian WuJinmei Li
Jun 21, 2018·Frontiers in Molecular Neuroscience·Li Zhang, Handong Wang
Jan 10, 2020·Current Pharmaceutical Design·Mohamed Adil A AMohammad Waseem
Oct 17, 2016·Essays in Biochemistry·Wolfgang VoosMichael Bruderek
Dec 20, 2018·Frontiers in Neurology·Adonis SferaCarolina Osorio
Dec 9, 2020·Journal of Alzheimer's Disease : JAD·Dona P W JayatungaRalph N Martins
Jun 12, 2021·Oxidative Medicine and Cellular Longevity·Sunao LiMingyang Zhang

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Methods Mentioned

BETA
biopsy
transgenic

Software Mentioned

Mieap

Related Concepts

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