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The promoter targeting sequence facilitates and restricts a distant enhancer to a single promoter in the Drosophila embryo

Development

Dec 20, 2002

Qing LinJumin Zhou

PMID: 12490558

Abstract

Transcriptional enhancers in large gene complexes activate promoters over huge distances, yet little is known about the mechanism of these long-range interactions. We report that the promoter targeting sequence (PTS) from the Abdominal-B locus of the Drosophila bithorax complex facilita...read more

Mentioned in this Paper

Embryo
Genes, Insect
Embryo Loss
Entire Embryo
Drosophila melanogaster Proteins
Complex (molecular entity)
Transcription, Genetic
Promoter
Drosophila
Abdomen
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The promoter targeting sequence facilitates and restricts a distant enhancer to a single promoter in the Drosophila embryo

Development

Dec 20, 2002

Qing LinJumin Zhou

PMID: 12490558

DOI:

Abstract

Transcriptional enhancers in large gene complexes activate promoters over huge distances, yet little is known about the mechanism of these long-range interactions. We report that the promoter targeting sequence (PTS) from the Abdominal-B locus of the Drosophila bithorax complex facilita...read more

Mentioned in this Paper

Embryo
Genes, Insect
Embryo Loss
Entire Embryo
Drosophila melanogaster Proteins
Complex (molecular entity)
Transcription, Genetic
Promoter
Drosophila
Abdomen

Similar Papers Found In These Feeds

Embryonic Development: Enhancer/Promoter(Keystone)

During development and differentiation of an organism, accurate gene regulation is central for cells to maintain and balance their differentiation processes. Transcriptional interactions between cis-acting DNA elements such as promoters and enhancers are the basis for precise and balanced transcriptional regulation.This feed follows research on enhancer promoter communication in embryonic development.

CREs: Gene & Cell Therapy

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.

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  • References
  • Citations31
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  • Citations31
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