The prophylactic effect of long-term lithium administration in bipolar patients entering treatment in the 1970s and 1980s

Bipolar Disorders
Janusz K RybakowskiAleksandra Suwalska

Abstract

The aim of the study was to assess the prophylactic effect of long-term lithium administration in patients with bipolar mood disorders entering treatment in the 1970s and 1980s at the outpatient clinic of the Department of Psychiatry, University of Medical Sciences, Poznan, Poland. The clinical characteristics of two groups of patients before and during lithium therapy were compared, namely, the 60 bipolar patients who entered lithium prophylaxis in the 1970s and 49 patients who entered in the 1980s. Both groups received the drug over a 10-year period. The patients who entered lithium in the 1970s had fewer previous episodes of depression and more of mania than the patients who entered the therapy in the 1980s, although the total number of affective episodes was similar in both groups. The overall prophylactic efficacy of lithium over a 10-year period of administration was similar in both groups, except for a trend towards a greater number of depressive episodes in the first year of lithium prophylaxis in the 1980s group. The excellent lithium responders constituted 35% of the 1970s patients and 27% of those in the 1980s group. The 1970s patients were maintained on a higher level of serum lithium compared to the patients in the...Continue Reading

References

Oct 1, 1989·The British Journal of Psychiatry : the Journal of Mental Science·H R Markar, A J Mander
Nov 30, 1989·The New England Journal of Medicine·A J GelenbergJ Lavelle
May 13, 1972·Lancet·R P HullinM N Allsopp
Aug 1, 1972·Psychological Medicine·R L CundallL G Murray
Sep 1, 1973·The American Journal of Psychiatry·F StalloneR R Fieve
Jun 1, 1970·The British Journal of Psychiatry : the Journal of Mental Science·P I Melia
Jun 1, 1994·The British Journal of Psychiatry : the Journal of Mental Science·R Guscott, L Taylor
Aug 1, 1996·The American Journal of Psychiatry·R E Johnson, B H McFarland
Jun 20, 1996·Journal of Affective Disorders·M MajL Magliano
Aug 1, 1997·The British Journal of Psychiatry : the Journal of Mental Science·J Moncrieff
Jul 8, 1998·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·P Grof
Jul 22, 1998·The Australian and New Zealand Journal of Psychiatry·G WalterR Kubb
Oct 10, 1998·Psychiatry and Clinical Neurosciences·Y Y YangB H Wang
Aug 5, 1999·European Archives of Psychiatry and Clinical Neuroscience·N KleindienstH J Möller
Feb 9, 2000·Archives of General Psychiatry·R J Baldessarini, L Tondo
Nov 1, 1963·The British Journal of Psychiatry : the Journal of Mental Science·G P HARTIGAN
Dec 1, 1964·Comprehensive Psychiatry·P C BAASTRUP

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Citations

Sep 4, 2012·Journal of Affective Disorders·Janusz K RybakowskiHagop H Akiskal
Jun 23, 2004·Journal of Affective Disorders·Steven Jones
May 1, 1984·Clinical and Experimental Pharmacology & Physiology·J RybakowskiC Nowakowska
May 18, 2005·Psychiatry and Clinical Neurosciences·Michael BerkLesley Berk
Jan 1, 2013·International Journal of Bipolar Disorders·Anne BerghöferAndrea Pfennig
Mar 17, 2007·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Eduard Vieta, Adriane R Rosa
Mar 3, 2011·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Janusz K Rybakowski
Apr 20, 2007·Journal of Affective Disorders·Julie GarnhamMartin Alda
Jan 1, 2004·Bipolar Disorders·Ari Zaretsky
Jun 23, 2009·Bipolar Disorders·Paul Grof, Bruno Müller-Oerlinghausen
Nov 12, 2010·Bipolar Disorders·Gin S Malhi
Mar 14, 2013·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Heinz GrunzeUNKNOWN WFSBP Task Force on Treatment Guidelines for Bipolar Disorders
May 16, 2014·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Ewa FerensztajnJanusz K Rybakowski
Apr 16, 2010·The International Journal of Neuropsychopharmacology·Janusz K Rybakowski, Aleksandra Suwalska
Apr 14, 2016·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Ewa Ferensztajn-RochowiakJanusz K Rybakowski
Mar 15, 2014·ACS Chemical Neuroscience·Janusz K Rybakowski
Sep 6, 2011·Journal of Psychopharmacology·Janusz K RybakowskiJoanna Hauser
Aug 19, 2016·Therapeutic Advances in Psychopharmacology·Agnieszka Permoda-OsipJanusz K Rybakowski
Jan 13, 2018·Bipolar Disorders·Janusz K Rybakowski
Jun 13, 2018·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Jeverson MoreiraCynthia Marie-Claire
Jul 3, 2019·Current Psychiatry Reports·Janusz K Rybakowski
Mar 25, 2020·Drug Development Research·Janusz K Rybakowski
Nov 8, 2014·Harvard Review of Psychiatry·Janusz K Rybakowski
Sep 24, 2020·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Ewa Ferensztajn-RochowiakJanusz K Rybakowski
Aug 10, 2005·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Roger S McIntyreVivek Kusumakar
Aug 26, 2016·The Australian and New Zealand Journal of Psychiatry·Sarah SporticheFrank Bellivier
Oct 20, 2018·Frontiers in Molecular Neuroscience·Janusz K Rybakowski
Feb 28, 2003·Psychopharmacology·Paolo BrambillaJair C Soares
Sep 14, 2004·CNS Spectrums·Claudia F BaldassanoJohn P O'Reardon
Feb 6, 2020·Focus : Journal of Life Long Learning in Psychiatry·Shani SternFred H Gage
Dec 8, 2009·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Martin Alda, Lakshmi N Yatham
Jul 6, 2012·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Cynthia Calkin, Martin Alda
May 26, 2018·Open Biology·Shani SternFred H Gage
Nov 11, 2020·International Journal of Psychiatry in Clinical Practice·Janusz K Rybakowski

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