Oct 1, 1977

The prospective evaluation of tumour-associated antigens for the early diagnosis of pancreatic cancer

The British Journal of Surgery
R A Wood, A R Moossa


An unselected series of 136 patients suspected of having a major intra-abdominal pathological condition had blood drawn and stored as serum. A definitive histological diagnosis was made in all cases, usually by laparotomy. The serum was analysed with coded samples for carcino-embryonic antigen, alpha-fetoprotein and pancreatic oncofetal antigen and all recorded levels above the upper limit of normal for that test were taken as a positive result. Results were analysed to give the predictive value of a positive test and a negative test for each antigen. A negative pancreatic oncofetal antigen test was found to be useful in excluding a diagnosis of pancreatic cancer.

Mentioned in this Paper

Pancreatic Carcinoma
Malignant Neoplasm of Pancreas
Tumor Lysis Syndrome
Carcinoembryonic Antigen
Embryonic antigen
Intraabdominal Infections
AFP gene
Pancreatic oncofetal antigen

About this Paper

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