The protective effect of salicylic acid on lysozyme against riboflavin-mediated photooxidation

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Kun LiShi-Long Wang

Abstract

As a metabolite of aspirin in vivo, salicylic acid was proved to protect lysozyme from riboflavin-mediated photooxidation in this study. The antioxidative properties of salicylic acid were further studied by using time-resolved laser flash photolysis of 355 nm. It can quench the triplet state of riboflavin via electron transfer from salicylic acid to the triplet state of riboflavin with a reaction constant of 2.25×10(9) M(-1) s(-1). Mechanism of antioxidant activities of salicylic acid on lysozyme oxidation was discussed. Salicylic acid can serve as a potential antioxidant to quench the triplet state of riboflavin and reduce oxidative pressure.

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Citations

Aug 1, 2015·ACS Applied Materials & Interfaces·Siyuan XieJingye Li
Jan 11, 2012·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·José NateraNorman A García
Mar 13, 2012·Food & Function·Daniel R CardosoLeif H Skibsted

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