The Pseudomonas syringae effector protein HopZ1a suppresses effector-triggered immunity.

The New Phytologist
Alberto P MachoCarmen R Beuzón

Abstract

*The Pseudomonas syringae pv syringae type III effector HopZ1a is a member of the HopZ effector family of cysteine-proteases that triggers immunity in Arabidopsis. This immunity is dependent on HopZ1a cysteine-protease activity, and independent of known resistance genes. We have previously shown that HopZ1a-triggered immunity is partially additive to that triggered by AvrRpt2. These partially additive effects could be caused by at least two mechanisms: their signalling pathways share a common element(s), or one effector interferes with the response triggered by the other. *Here, we investigate the molecular basis for the partially additive effect displayed by AvrRpt2- and HopZ1a-triggered immunities, by analysing competitive indices, hypersensitive response and symptom induction, PR-1 accumulation, expression of PR genes, and systemic acquired resistance (SAR) induction. *Partially additive effects between these defence responses require HopZ1a cysteine-protease activity, and also take place between HopZ1a and AvrRps4 or AvrRpm1-triggered responses. We establish that HopZ1a-triggered immunity is independent of salicylic acid (SA), EDS1, jasmonic acid (JA) and ethylene (ET)-dependent pathways, and show that HopZ1a suppresses the...Continue Reading

References

Dec 1, 1992·Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases·J Goto
Jun 5, 1983·Journal of Molecular Biology·D Hanahan
May 1, 1995·Molecular Plant-microbe Interactions : MPMI·C Ritter, J L Dangl
Nov 1, 1995·Molecular Plant-microbe Interactions : MPMI·K LawtonJ Ryals
Aug 26, 1998·Proceedings of the National Academy of Sciences of the United States of America·N AartsJ E Parker
Dec 23, 1998·Proceedings of the National Academy of Sciences of the United States of America·D C BoyesJ L Dangl
Nov 11, 1999·Proceedings of the National Academy of Sciences of the United States of America·D JirageJ Glazebrook
Jul 13, 2000·Proceedings of the National Academy of Sciences of the United States of America·S C van WeesC M Pieterse
Dec 6, 2000·Molecular Plant-microbe Interactions : MPMI·Z ChenB N Kunkel
Jul 3, 1995·Proceedings of the National Academy of Sciences of the United States of America·K S CenturyB J Staskawicz
Feb 16, 2002·Science·Cristina AzevedoPaul Schulze-Lefert
Jun 13, 2002·The Plant Journal : for Cell and Molecular Biology·Marta Berrocal-LoboRoberto Solano
Oct 1, 1996·The Plant Cell·J. A. RyalsM. D. Hunt
Feb 6, 2004·The Plant Journal : for Cell and Molecular Biology·Zhongying ChenBarbara N Kunkel
Jun 18, 2004·Immunological Reviews·Thorsten NürnbergerLizelle Piater
Sep 28, 2004·The Plant Journal : for Cell and Molecular Biology·Peter CoppingerBrian J Staskawicz
Oct 8, 2004·Cellular Microbiology·Avelina Espinosa, James R Alfano
Nov 18, 2004·The Plant Journal : for Cell and Molecular Biology·Melisa T S Lim, Barbara N Kunkel
Apr 23, 2005·Proceedings of the National Academy of Sciences of the United States of America·Han-Suk KimJeffery L Dangl

❮ Previous
Next ❯

Citations

Jan 30, 2013·Journal of Genetics and Genomics = Yi Chuan Xue Bao·Yan ZhangMingliang Xu
Jul 6, 2011·Molecular Plant Pathology·Jennifer D LewisDarrell Desveaux
Aug 17, 2010·The New Phytologist·Francis Martin
Dec 15, 2010·Plant Signaling & Behavior·Alberto P Macho, Carmen R Beuzón
May 12, 2016·Seminars in Cell & Developmental Biology·Karl J SchreiberJennifer D Lewis
Jul 29, 2017·PloS One·Laura Medina-PuchePablo Tornero
Dec 22, 2017·The Plant Journal : for Cell and Molecular Biology·Jonathan M Plett, Francis M Martin
Oct 28, 2016·Microbiology and Molecular Biology Reviews : MMBR·Ka-Wai Ma, Wenbo Ma
Sep 27, 2019·The Plant Journal : for Cell and Molecular Biology·Maël BaudinJennifer D Lewis
Feb 6, 2020·Metabolites·Fernanda R Castro-MorettiAna P Alonso
Jan 26, 2020·Plants·Loredana ScalschiBegonya Vicedo
Feb 28, 2019·Plant Methods·José S RufiánJavier Ruiz-Albert
Aug 30, 2018·Frontiers in Plant Science·José S RufiánJavier Ruiz-Albert
Mar 23, 2021·Frontiers in Plant Science·Feng YangJinliang Liu
Apr 11, 2021·Proceedings of the National Academy of Sciences of the United States of America·Lulu LiZongtao Sun
May 8, 2021·The New Phytologist·José S RufiánJavier Ruiz-Albert
Sep 18, 2021·Plant, Cell & Environment·Xiaoli LiuDousheng Wu
Aug 1, 2020·Cell Host & Microbe·Liu XianAlberto P Macho

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.