PMID: 8947454Dec 1, 1996Paper

The pulsatile impeller pump for left ventricular assist

Artificial Organs
S S WangK X Qian

Abstract

Because of severe hemolysis, especially on producing pulsatile flow by changing the rotating speed of the impellers, the traditional centrifugal pump was rarely used for long-term support of the failing heart. We therefore developed a motor driven pulsatile implantable impeller pump. The pulsatility was achieved by changing the rotating speed via introducing a square waveform voltage into the motor coil. The impeller vane was designed to have both radial and axial curves according to the stream surface and stream lines to reduce the thrombosis and hemolysis. Nine calves weighing 80 to 100 kg were used. With the calves under endotracheal general anesthesia, left posterolateral thoracotomy was performed to connect the inflow tube with the left atrial appendage and to anastomose the outflow tube with the descending aorta. The calves usually awoke and stood up within hours after discontinuation of anesthetics. Within 7 days, continuous monitoring of electrocardiogram, systemic and pulmonary arterial pressures, and central venous pressure were performed to adjust the pump flow to 40% to 50% of the cardiac output. During the survival of 4 to 54 days (mean 16.3 +/- 19.3 days with two calves surviving longer than 1 month), no significa...Continue Reading

References

Nov 1, 1990·Journal of Biomedical Engineering·K X Qian
May 1, 1986·Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Für Medizinische Physik and the European Federation of Organisations for Medical Physics·B Sethia, D J Wheatley
Jan 1, 1971·The American Journal of Cardiology·M E DeBakey

❮ Previous
Next ❯

Citations

Dec 18, 2003·Artificial Organs·Stijn VandenberghePascal Verdonck
Dec 22, 2009·Artificial Organs·Wei WangWen-Xiang Ding
Nov 24, 2004·Artificial Organs·Jeou-Jong ShyuShu-Hsun Chu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cajal Bodies & Gems

Cajal bodies or coiled bodies are dense foci of coilin protein. Gemini of Cajal bodies, or gems, are microscopically similar to Cajal bodies. It is believed that Cajal bodies play important roles in RNA processing while gems assist the Cajal bodies. Find the latest research on Cajal bodies and gems here.