The pupillary light reflex in normal and innate microstrabismic cats, I: Behavior and receptive-field analysis in the nucleus praetectalis olivaris

Visual Neuroscience
C Distler, K P Hoffmann

Abstract

Neurons in the nucleus praetectalis olivaris (NPO) were antidromically identified by electrical stimulation of the nucleus of Edinger-Westphal (EW), the location of preganglionic pupilloconstrictor motoneurons. Electrical stimulation within the NPO leads to bilateral pupil constriction. Single neurons recorded in the NPO respond tonically to light stimuli, and their discharge frequency increases linearly with logarithmic increase in light intensity. This characteristic identifies NPO neurons as luminance detectors. They have large receptive fields mostly lying in the upper and contralateral quadrant of the visual field. Cats with impaired binocular vision show a significantly reduced binocular summation of the pupillary light reflex (BSP), i.e. the increase of pupil constriction during binocular illumination when compared to monocular illumination is less than in normal animals. The investigation of ocular dominance and subthreshold binocular interactions in the NPO of normal and innate microstrabismic cats revealed two possible mechanisms for BSP and its reduction in strabismic subjects. First, the percentage of neurons increasing their discharge rate by illuminating either eye is significantly reduced in the NPO of innate mic...Continue Reading

References

Jul 15, 1977·The Journal of Comparative Neurology·N Berman
Jan 5, 1979·Brain Research·H J Steiger, J A Büttner-Ennever
Dec 29, 1978·Brain Research·H HultbornN Tsukahara
Oct 14, 1985·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·G Campbell, A R Lieberman
Jun 1, 1985·The Journal of Comparative Neurology·M A KoontzS G Farmer
Dec 1, 1985·Archives of Ophthalmology·P Romano, M Michels
Jun 1, 1973·The Journal of Comparative Neurology·M B Carpenter, R J Pierson
Nov 15, 1974·The Journal of Comparative Neurology·R J Pierson, M B Carpenter
Oct 1, 1969·Experimental Neurology·M Straschill, K P Hoffmann
Dec 1, 1974·The Journal of Comparative Neurology·T Kanaseki, J M Sprague
Aug 1, 1967·Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology·E Alexandridis, E Dodt
Nov 1, 1965·Journal of Neurophysiology·D H Hubel, T N Wiesel
May 1, 1967·Journal of Neurophysiology·J ten Doesschate, M Alpern
Jan 1, 1984·Experimental Brain Research·K P Hoffmann, A Schoppmann
Jul 13, 1984·Neuroscience Letters·H ImaiS Kuchiiwa
Nov 14, 1983·Brain Research·J T Dineen, A Hendrickson
Jul 10, 1984·The Journal of Comparative Neurology·P D GamlinD H Cohen
Sep 1, 1980·The Journal of Comparative Neurology·C Avendaño, M A Juretschke
Sep 9, 1982·Brain Research·K ShoumuraK Sukekawa
Jan 1, 1981·Brain Research·M Cynader, K P Hoffmann
Dec 1, 1962·The Journal of Physiology·M ALPERN, F W CAMPBELL
Dec 1, 1949·The Journal of Comparative Neurology·H KUHLENBECK, R N MILLER

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Citations

Aug 31, 2004·BMC Neuroscience·Nora Prochnow, Matthias Schmidt
Sep 7, 2006·Experimental Brain Research·Robert J Clarke
Jan 1, 1992·The European Journal of Neuroscience·M. Schmidt, K.-P. Hoffmann
Dec 22, 2004·The European Journal of Neuroscience·Gesche Born, Matthias Schmidt
Jan 1, 1991·Visual Neuroscience·C Distler, K P Hoffmann
Apr 28, 1997·The Journal of Comparative Neurology·H D Kourouyan, J C Horton
Oct 17, 2018·Investigative Ophthalmology & Visual Science·Marija ZivcevskaAgnes M F Wong
Sep 5, 2007·The European Journal of Neuroscience·Gesche Born, Matthias Schmidt
Oct 1, 1995·The European Journal of Neuroscience·K M ChanR D Lund
Mar 4, 2003·Journal of Neurophysiology·Robert J ClarkePaul D R Gamlin
Apr 8, 2014·The Journal of Comparative Neurology·Wensi Sun, Paul J May
Dec 19, 2019·Brain Structure & Function·Paul J May, Susan Warren
Sep 24, 2020·Cellular and Molecular Life Sciences : CMLS·Marcos L Aranda, Tiffany M Schmidt
Mar 1, 1995·Visual Neuroscience·J B TroyC Enroth-Cugell
Dec 26, 2019·Brain Structure & Function·Paul J MayJonathan T Erichsen
Nov 24, 2015·Annual Review of Vision Science·Onkar S DhandeAndrew D Huberman

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