The puzzling question of inhibitory control in Tourette syndrome: A meta-analysis

Neuroscience and Biobehavioral Reviews
Simon Morand-BeaulieuMarc E Lavoie

Abstract

Tourette syndrome (TS) is a neuropsychiatric disorder involving motor and phonic tics. Inhibitory control is a key issue in TS, and many disruptive or impulsive behaviors might arise from inhibitory deficits. However, conflicting findings regarding TS patients' inhibitory performance in neuropsychological tasks have been reported throughout the literature. Therefore, this meta-analysis aimed to evaluate inhibitory control through neuropsychological tasks, and to analyze the factors modulating inhibitory deficits. To this end, a literature search was performed through MEDLINE and PsycINFO, to retrieve studies including neuropsychological tasks that assessed inhibitory control in TS patients. Of the 4020 studies identified, 61 were included in the meta-analysis, for a total of 1717 TS patients. Our analyses revealed a small to medium effect in favor of inhibitory deficits in TS patients. This effect was larger in TS+ADHD patients, but pure TS patients also showed some inhibitory deficits. Therefore, deficits in inhibitory control seem to be an inherent component of TS, and are exacerbated when ADHD is concomitant.

Citations

Feb 28, 2018·Journal of Attention Disorders·Defeng XuYufeng Wang
May 22, 2018·Movement Disorders : Official Journal of the Movement Disorder Society·Christian ManciniGiovanni Mirabella
Jan 10, 2018·CNS Neuroscience & Therapeutics·Andrea SantangeloMaurizio Casarrubea
Mar 7, 2018·Movement Disorders : Official Journal of the Movement Disorder Society·Christos GanosPatrick Haggard
Nov 1, 2018·Movement Disorders : Official Journal of the Movement Disorder Society·Christos GanosJohn Rothwell
Jul 20, 2019·Journal of Child Neurology·Harvey S Singer, Farhan Augustine
Nov 4, 2017·European Child & Adolescent Psychiatry·Erica GreenbergUNKNOWN Tourette Association of America International Consortium for Genetics
Oct 3, 2019·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Hugues LamotheAntoine Pelissolo
Jan 25, 2018·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Navkiran KalsiCarlo Lai
Mar 24, 2020·Brain : a Journal of Neurology·Georgina M Jackson, Stephen R Jackson
Apr 15, 2020·Expert Opinion on Pharmacotherapy·Nicholas CothrosTamara Pringsheim
May 7, 2020·Cognitive Neuropsychiatry·Andrea E CavannaStefano Seri
Aug 22, 2020·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Thaïra J C OpenneerAndrea Dietrich
Sep 14, 2018·F1000Research·Andreas HartmannKevin J Black
Mar 13, 2020·Frontiers in Psychiatry·Lille KurvitsChristos Ganos
Aug 19, 2017·Brain Sciences·Simon Morand-BeaulieuBruno Gauthier
Jun 27, 2019·Journal of Child Neurology·Soyoung KimKevin J Black
Nov 30, 2018·Movement Disorders : Official Journal of the Movement Disorder Society·Max-Philipp StennerKirsten R Müller-Vahl
Oct 1, 2020·Molecular Psychiatry·Cyril Atkinson-ClementYulia Worbe
Nov 17, 2020·Frontiers in Neurology·Federica GraziolaAlessandro Capuano
Dec 15, 2020·The European Journal of Neuroscience·Lorenz GoennerFred H Hamker
Nov 28, 2020·Frontiers in Neurology·Maximilian KleimakerAlexander Münchau
Mar 2, 2021·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·E QuadrelliC Termine
Mar 22, 2021·Child and Adolescent Psychiatric Clinics of North America·Marianna AshurovaBarbara J Coffey
Jan 25, 2020·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Cyril Atkinson-ClementYulia Worbe
Apr 18, 2021·Clinical Psychology Review·Amitai AbramovitchAvraham Schweiger
May 16, 2021·Biological Psychiatry : Cognitive Neuroscience and Neuroimaging·Simon Morand-BeaulieuDenis G Sukhodolsky
Jun 19, 2021·PloS One·Canan Beate SchüllerJens Kuhn
Jun 23, 2021·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Joseph F McGuireJohn Piacentini
Jun 29, 2021·Current Developmental Disorders Reports·Keisuke UedaKevin J Black
Jul 31, 2021·Nature Reviews. Neuroscience·Ricci Hannah, Adam R Aron

❮ Previous
Next ❯

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.

Related Papers

The Johns Hopkins Medical Journal
H S Singer
JAMA : the Journal of the American Medical Association
Christopher C Muth
Advances in Neurology
Thomas J SpencerT Wilens
© 2022 Meta ULC. All rights reserved