The quality of evidence in Chinese meta-analyses needs to be improved

Journal of Clinical Epidemiology
Liang YaoKehu Yang

Abstract

We conducted a systematic review using GRADE (Grading of Recommendations Assessment, Development and Evaluation) system to assess the quality of evidence of Chinese meta-analyses (MAs). A systematic review of MAs listed in Chinese Biomedicine Literature Database from January 2010 to December 2012. Mesh term "meta-analysis" was used to search the Chinese Biomedicine Literature Database from January 2010 to December 2012. Characteristics and main outcomes of each included MA were extracted, and the GRADE system was used to assess the quality of evidence for each outcome. A 10% random sample of Cochrane MAs between 2010 and 2012 was also assessed as control group. A total of 564 Chinese MAs (including 1,237 main outcomes) and 95 Cochrane MAs (including 251 main outcomes) were identified. Almost half (600, 48.5%) of the outcomes in Chinese MAs were rated as low, and the proportion of outcomes with high or moderate quality of evidence was lower in Chinese MAs than Cochrane MAs (Chinese, 406 [32.8%] vs. Cochrane MAs, 155 [61.8%], P < 0.001). Of the outcomes in Chinese MAs, 1,012 (81.8%) were downgraded for risk of bias. Other common factors for downgrading were imprecision (448, 36.2%), publication bias (418, 33.8%), inconsistency (3...Continue Reading

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Citations

Feb 10, 2019·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Dacheng JinYunjiu Gou
Nov 26, 2019·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Meng WangJie Qiu
Jan 3, 2020·Clinical and Experimental Medicine·Ya GaoUNKNOWN Cancer Biomarker Assessment Working Group
Jan 5, 2019·Archives of Gynecology and Obstetrics·Xiaqin HuoHuiling Liu
Nov 22, 2019·World Journal of Clinical Cases·Ke-Lu YangJin-Hui Tian
Jan 11, 2020·Frontiers in Public Health·Cuncun LuKehu Yang
Jun 14, 2019·Medicine·Zhijuan ShengUNKNOWN Cancer Biomarker Assessment Working Group
Apr 5, 2017·Evidence-based Complementary and Alternative Medicine : ECAM·Shuo FengJian-Ping Liu
Jun 7, 2019·The Journal of Clinical Hypertension·Liujiao CaoKehu Yang
Apr 5, 2020·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Y BaoK Yang
Jun 9, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Jinke HuangYong Huang
May 15, 2019·Medicine·Fanqi WuUNKNOWN Cancer Biomarker Assessment Working Group
Jun 11, 2020·Health and Quality of Life Outcomes·Juan LiYingdong Li

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