The quality of life in patients with a different types of myasthenia gravis

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Yu N BykovA I Smolin

Abstract

Researching quality of life in patients with myasthenia gravis at different clinical variants of disease. We studied 103 patients with myasthenia gravis. A battery of tests and scales for assessment of neurological deficit and quality of life was used. Two types of disease have been identified in myasthenia gravis: favorable and unfavorable. The minimal duration of disease before thymectomy is the main determinant of the best outcome. Favorable clinical type of myasthenia gravis was found in patients with weakness in extraocular and limb muscles. Factors associated with a poor quality of life included following: weakness in bulbar and respiratory muscles (p<0.003), endocrine comorbidities (p<0.01) or thymoma (p<0.005).

References

Jul 21, 1998·Annals of the New York Academy of Sciences·R J BarohnW W Bryan
Dec 7, 2007·Muscle & Nerve·David GrobMurali Pagala
Feb 5, 2010·Neuroepidemiology·Anita McGroganCorinne S de Vries
Jun 23, 2010·BMC Neurology·Aisling S CarrJohn McConville
May 15, 2012·Muscle & Nerve·Anne Taraldsen HeldalFredrik Romi
Apr 29, 2015·Muscle & Nerve·Julie S HansenHenning Andersen

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