PMID: 2487609Jan 1, 1989Paper

The race effect

Clinical Transplants
J Yuge, J M Cecka

Abstract

1. One-year graft survival rates were 93% for recipients of HLA-identical sibling transplants in Blacks and Caucasians. One-year graft survival rates were lower in Blacks than Caucasians by 6% for parent donor, 8% for first cadaver, and 4% for cadaver donor retransplants between 1984 and 1989. 2. Although 1-year graft survival was consistently lower in Black recipients, there was no significant race difference when the recipient was over age 45 years. In transplants performed after 1986, there was no significant race difference when the recipient was over age 30 years. 3. Black recipients aged 15-30 years had the poorest 1-year graft survival at 64% each year between 1984 and 1988. One-year graft survival in comparable Caucasian recipients improved from 73-82% during this interval. The difference was greatest (18%) when comparing young Black and Caucasian males. 4. Caucasians had better early function than Blacks as judged from serum creatinine levels in the first 60 days. Fifty-two percent of Caucasians had excellent function (SCr less than 1.5 mg/dl) vs 37% of Blacks. Conversely, 22% of Blacks had SCr levels that never fell below 2.5 mg/dl vs 16% of Caucasians. There was no racial difference in early graft survival when trans...Continue Reading

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