The radiation oncology ontology (ROO): Publishing linked data in radiation oncology using semantic web and ontology techniques

Medical Physics
Alberto TraversoAndre Dekker

Abstract

Personalized medicine is expected to yield improved health outcomes. Data mining over massive volumes of patients' clinical data is an appealing, low-cost and noninvasive approach toward personalization. Machine learning algorithms could be trained over clinical "big data" to build prediction models for personalized therapy. To reach this goal, a scalable "big data" architecture for the medical domain becomes essential, based on data standardization to transform clinical data into FAIR (Findable, Accessible, Interoperable and Reusable) data. Using Ontologies and Semantic Web technologies, we attempt to reach mentioned goal. We developed an ontology to be used in the field of radiation oncology to map clinical data from relational databases. We combined ontology with semantic Web techniques to publish mapped data and easily query them using SPARQL. The Radiation Oncology Ontology (ROO) contains 1,183 classes and 211 properties between classes to represent clinical data (and their relationships) in the radiation oncology domain following FAIR principles. We combined the ontology with Semantic Web technologies showing how to efficiently and easily integrate and query data from different (relational database) sources without a prio...Continue Reading

References

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Citations

Oct 12, 2018·Current Hematologic Malignancy Reports·Nour Abuhadra, Aziz Nazha
Oct 4, 2019·Medical Physics·Zhenwei ShiLeonard Wee
Sep 19, 2019·NPJ Digital Medicine·Maulik R KamdarMark A Musen
Jan 9, 2020·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Timo M DeistAndre Dekker
Feb 6, 2021·International Journal of Radiation Oncology, Biology, Physics·Danielle S BittermanGuergana K Savova
Feb 28, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Petros KalendralisRianne Fijten
Apr 28, 2019·Seminars in Radiation Oncology·Jolien Heukelom, Clifton David Fuller
Oct 28, 2019·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·A Burgun
May 1, 2021·American Society of Clinical Oncology Educational Book·Lisanne V van Dijk, Clifton D Fuller
May 6, 2021·BMC Medical Informatics and Decision Making·Pilar López-ÚbedaStefan Schulz
Jul 27, 2021·Physics and Imaging in Radiation Oncology·Matthew FieldLois Holloway
Aug 10, 2021·Physical and Engineering Sciences in Medicine·Lois HollowayClive Baldock
Nov 2, 2021·Journal of Digital Imaging·Ross W Filice, Charles E Kahn

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