The radiosensitive effect of apatinib for hepatocellular carcinoma patient with big paraspinal metastasis: A case report

Medicine
Hong ZhuXin Wang

Abstract

Hepatocellular carcinoma (HCC) is a highly invasive cancer associated with great mortality rates. The prognosis of advanced HCC is very poor. Here, we report a HCC patient with a big paraspinal metastasis with 10 cm in diameter who failed the treatment of sorafenib. Sorafenib refractory HCC with big paraspinal metastasis. The concurrent treatment of apatinib with stereotactic body radiotherapy (SBRT). The paraspinal metastasis with 10 cm in diameter showed nearly complete response. We think that the apatinib may be a good choice for HCC and it may function as a radiosensitizer of HCC. However, it warrants further investigation in the future prospective clinical studies.

References

Jul 25, 2008·The New England Journal of Medicine·Josep M LlovetUNKNOWN SHARP Investigators Study Group
Jan 25, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Yu-Tse TsanPau-Chung Chen
Aug 7, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jin LiHao Yu

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