The rare solid fetal lung lesion with T2-hypointense components: prenatal imaging findings with postnatal pathological correlation

Pediatric Radiology
Teresa VictoriaN Scott Adzick

Abstract

At fetal MR, congenital lung lesions are usually T2 hyperintense with respect to normal lung parenchyma. Some lesions, however, demonstrate unusual patterns of T2 hypointensity, sometimes in a rosette-like pattern. These lesions usually present a diagnostic conundrum. To evaluate the imaging findings and pathological characterization of fetal solid lung lesions with elements showing T2-hypointense signal with respect to lung. This is a retrospective study of lung lesions with elements showing T2 hypointensity treated prenatally and postnatally at our center and with available pathological evaluation. Prenatal imaging evaluation included US and MR; postnatal evaluation consisted of pathological examination of the lesion. We also performed prenatal and postnatal chart review. Six cases met study criteria. Areas of decreased echogenicity/T2-hypointense signal were more conspicuous at MR than US. At pathology, these areas correlated with immature parenchymal development and increased mesenchymal tissue. Five of these lesions were congenital pulmonary airway malformations (CPAM); one was a congenital peribronchial myofibroblastic tumor (CPMT). The lesions did not significantly change in size after steroid administration. They were a...Continue Reading

References

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Citations

Jan 12, 2020·Prenatal Diagnosis·Teresa VictoriaN Scott Adzick
Dec 1, 2020·Pediatric Radiology·Niamh C AdamsGabrielle C Colleran
Mar 11, 2021·Pediatric Radiology·Beverley Newman

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