The rational use of pituitary stimulation tests.

Deutsches Ärzteblatt International
S PetersennMichael Buchfelder

Abstract

Diseases of the pituitary gland can lead to the dysfunction of individual hormonal axes and to the corresponding clinical manifestations. The diagnostic assessment of pituitary function has not yet been standardized. The members of the Neuroendocrinology Section and the Pituitary Study Group of the German Society for Endocrinology (Deutsche Gesellschaft für Endokrinologie) prepared outlines of diagnostic methods for the evaluation of each of the pituitary hormonal axes. These outlines were discussed in open session in recent annual meetings of the Section and the Study Group. For the evaluation of the thyrotropic axis, basal TSH and free T4 usually suffice. For the evaluation of the gonadotropic axis in men, the testosterone level should be measured; if the overall testosterone level is near normal, then calculating the free testosterone level may be additionally useful. In women, an intact menstrual cycle is sufficient proof of normal function. In the absence of regular menstruation, measurement of the basal estradiol and gonadotropin levels aids in the diagnosis of the disturbance. For the evaluation of the adrenocorticotropic axis, the basal cortisol level may be helpful; provocative testing is in many cases necessary for pr...Continue Reading

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Citations

Apr 24, 2018·International Journal of Endocrinology·José Gerardo González-GonzálezRené Rodríguez-Gutiérrez
Oct 11, 2020·Headache·Sandhya MehlaRandolph W Evans
Mar 8, 2018·Deutsches Ärzteblatt International·Matthias K AuerAnna Kopczak

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