The Rationale for Performance of Coronary Angiography and Stenting Before Transcatheter Aortic Valve Replacement: From the Interventional Section Leadership Council of the American College of Cardiology

JACC. Cardiovascular Interventions
Stephen RameeInterventional Section of the Leadership Council of the American College of Cardiology


Transcatheter aortic valve replacement (TAVR) is an effective, nonsurgical treatment option for patients with severe aortic stenosis. The optimal treatment strategy for treating concomitant coronary artery disease (CAD) has not been tested prospectively in a randomized clinical trial. Nevertheless, it is standard practice in the United States to perform coronary angiography and percutaneous coronary intervention for significant CAD at least 1 month before TAVR. All existing clinical trials were designed using this strategy. Therefore, it is wrong to extrapolate current American College of Cardiology/American Heart Association Appropriate Use Criteria against invasive procedures in asymptomatic patients to the TAVR population when evaluating the quality of care by cardiologists or hospitals. In this statement from the Interventional Section Leadership Council of the ACC, it is recommended that percutaneous coronary intervention should be considered in all patients with significant proximal coronary stenosis in major coronary arteries before TAVR, even though the indication is not covered in current guidelines.


Apr 1, 2014·The New England Journal of Medicine·David H AdamsUNKNOWN U.S. CoreValve Clinical Investigators
Feb 13, 2016·Nature Reviews. Cardiology·Edward DansonRavinay Bhindi
Feb 27, 2016·Journal of the American College of Cardiology·Tarun ChakravartyRaj R Makkar

❮ Previous
Next ❯


Mar 7, 2018·Current Treatment Options in Cardiovascular Medicine·Konstantinos V VoudrisKonstantinos Charitakis
Mar 1, 2018·Interactive Cardiovascular and Thoracic Surgery·Benedikt MayrMarcus-André Deutsch
Aug 8, 2018·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Jacob LønborgLars Søndergaard
May 14, 2018·Journal of the American Heart Association·Toby RogersRon Waksman
Oct 13, 2018·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Jun LiGuilherme F Attizzani
Dec 5, 2018·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Paul GuedeneyUNKNOWN WIN TAVI Investigators
Aug 28, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Arnav KumarHabib Samady
Apr 24, 2018·Current Treatment Options in Cardiovascular Medicine·Vikas SinghWilliam W O'Neill
Sep 29, 2017·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·R J de Winter
Dec 10, 2019·Circulation·Abdulla A DamlujiUNKNOWN American Heart Association Council on Clinical Cardiology and Council on Cardiovascular and Stroke Nursing
Mar 11, 2021·Expert Review of Cardiovascular Therapy·Silvia FrattiniPompilio Faggiano
Mar 21, 2020·JACC. Cardiovascular Interventions·Toby RogersRon Waksman
Feb 25, 2019·Journal of Cardiothoracic and Vascular Anesthesia·Oscar D Aljure, Michael Fabbro
Mar 31, 2021·Revista Española De Cardiología·Alfredo RedondoIgnacio J Amat-Santos
Apr 20, 2021·European Heart Journal·UNKNOWN VARC-3 WRITING COMMITTEEMartin B Leon
Apr 24, 2021·Journal of the American College of Cardiology·UNKNOWN VARC-3 WRITING COMMITTEE:Martin B Leon

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.