The rationale for third trimester testing of vertical HIV transmission in neonates with CMV infection

Infection
Vinzenz BoosChristof Dame

Abstract

We report on a late-preterm neonate with severe congenital cytomegalovirus (CMV) infection, refractory to antiviral therapy with ganciclovir. Subsequent immune diagnostics led to the finding of HIV infection at day 69, even though the mother tested negative for HIV in early pregnancy. Thus, in congenital CMV infection, HIV testing should be performed to elucidate maternal HIV seroconversion during late pregnancy. Our case strongly supports third trimester screening of HIV infection acquired during pregnancy, yet recommended only for women with traditional risk factors for HIV or living in an area of high HIV prevalence.

References

Apr 24, 2001·Journal of Acquired Immune Deficiency Syndromes : JAIDS·A RoongpisuthipongUNKNOWN Bangkok Collaborative Perinatal HIV Transmission Study Group
Aug 29, 2001·Journal of Tropical Pediatrics·W RouxM Cotton
Jun 21, 2007·Reviews in Medical Virology·Aileen Kenneson, Michael J Cannon
Dec 7, 2007·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·S E MosesM Zuckerman
Feb 19, 2008·The Journal of Infectious Diseases·David W KimberlinUNKNOWN National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group
Sep 22, 2009·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Sara E OliverUNKNOWN National Institute of Allergy, Infectious Diseases Collaborative Antiviral Study Group
May 1, 2010·The Pediatric Infectious Disease Journal·Elaine L DuryeaElizabeth K Stehel
Dec 24, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Leigh F JohnsonGayle G Sherman
May 26, 2012·Journal of the International Association of Physicians in AIDS Care : JIAPAC·Sahar Faghih, Elizabeth Secord
Jun 8, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Toni FrederickAndrea Kovacs
Nov 23, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Nyaxewo MwaanzaMatthew Bates

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Citations

Jun 4, 2017·Infection·Malihe Nourollahpour ShiadehAli Rostami

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