PMID: 9003801Jan 13, 1997Paper

The reaction mechanism of phosphomannomutase in plants

FEBS Letters
C OesterheltW Gross

Abstract

The enzyme phosphomannomutase catalyzes the interconversion of mannose-1-phosphate (Man-1-P) and mannose-6-phosphate (Man-6-P). In mammalian cells the enzyme has to be activated by transfer of a phosphate group from a sugar-1.6-P2 (Guha, S.K. and Rose, Z.B. (1985) Arch. Biochem. Biophys. 243, 168). In contrast, in the red alga Galdieria sulphuraria the co-substrate (Man-1.6-P2 or Glc-1.6-P2) is converted to the corresponding sugar monophosphate while the substrate is converted to the sugar bisphosphate in each reaction cycle. Evidence is presented that the same reaction mechanism occurs in spinach and yeast.

Citations

May 7, 1999·European Journal of Biochemistry·L JollyD Mengin-Lecreulx
May 5, 2001·Annual Review of Plant Physiology and Plant Molecular Biology·Nicholas SmirnoffFrank A Loewus
Jul 4, 2018·The Biochemical Journal·Olawale G RaimiDaan M F van Aalten
Jan 13, 2006·Yeast·Sławomir MilewskiJarosław Olchowy
Nov 4, 2020·Nature Communications·Henry P WoodJonathan P Waltho
Sep 12, 2006·Journal of Molecular Biology·Lukasz KedzierskiEmanuela Handman

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