The 'real-life' COPD patient in Germany: The DACCORD study

Respiratory Medicine
Heinrich WorthClaus Vogelmeier

Abstract

DACCORD is an ongoing, longitudinal, non-interventional study within the German COPD National Prospective Registry. This manuscript describes the baseline characteristics of the first 5924 participants, recruited between November 2012 and November 2013. The main inclusion criteria are a physician diagnosis of COPD, age ≥40 years, and initiating or changing COPD maintenance medication. Data collected included: Demographic and disease characteristics; prescribed medication; symptoms; COPD Assessment Test (CAT); modified Medical Research Council dyspnoea score (mMRC); exacerbations; comorbidities; and forced expiratory volume in 1 s (FEV1). Approximately 60% of the population are male, with mean age of 65.7 years and FEV1 61.6% predicted. On entry to the study the majority of patients reported symptoms, most commonly exertional dyspnoea (85.9%) and cough (65.7%). According to GOLD 2010, 48.6% of patients were classified as GOLD II. GOLD 2011 classification was influenced by the symptoms criterion: 43.7 and 45.3% of patients were classified as GOLD B or D using CAT, compared with 26.4 and 34.0%, respectively, using mMRC. The majority of patients were receiving a LAMA-containing regimen, with 39.4% overall receiving ICS. A total of ...Continue Reading

References

Nov 30, 2006·PLoS Medicine·Colin D Mathers, Dejan Loncar
Feb 23, 2007·The New England Journal of Medicine·Peter M A CalverleyUNKNOWN TORCH investigators
Oct 6, 2007·American Journal of Respiratory and Critical Care Medicine·Jadwiga A WedzichaUNKNOWN INSPIRE Investigators
Oct 7, 2008·The New England Journal of Medicine·Donald P TashkinUNKNOWN UPLIFT Study Investigators
Apr 1, 2009·The American Journal of Medicine·R Graham BarrGerard M Turino
May 21, 2010·Respiratory Medicine·Luis A García RodríguezSaga Johansson
Sep 10, 2010·Pneumologie·R PritzkuleitA Katalinic
Dec 22, 2012·The European Respiratory Journal·Paul W JonesNorbert Banik
Jun 15, 2013·The European Respiratory Journal·Alvar AgustiUNKNOWN ECLIPSE Investigators
Nov 2, 2013·The European Respiratory Journal·John HaughneyLorcan McGarvey
Dec 11, 2013·The Lancet. Respiratory Medicine·MeiLan K HanBarry J Make
Jul 27, 2014·The European Respiratory Journal·Anouk W VaesMartijn A Spruit
Sep 12, 2014·International Journal of Chronic Obstructive Pulmonary Disease·David PriceKatsiaryna Bichel
Feb 6, 2015·International Journal of Chronic Obstructive Pulmonary Disease·Josefin SundhThomas Sandström

❮ Previous
Next ❯

Citations

May 7, 2016·Postgraduate Medicine·Pavlina A Andreeva-GatevaTzvetelin Gatev
Oct 3, 2018·American Journal of Respiratory and Critical Care Medicine·Peter Kardos
Nov 1, 2017·MMW Fortschritte der Medizin·A GillissenMaria Paparoupa
Feb 23, 2020·NPJ Primary Care Respiratory Medicine·Ioanna Tsiligianni, Janwillem W H Kocks
Nov 9, 2017·COPD·Marco ContoliNicola Scichilone
Nov 28, 2020·Advances in Therapy·John R HurstMark T Dransfield
Sep 11, 2021·NPJ Primary Care Respiratory Medicine·Miguel Román-Rodríguez, Janwillem W H Kocks

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.