The Real-World Cost-Effectiveness of Coronary Artery Bypass Surgery Versus Stenting in High-Risk Patients: Propensity Score-Matched Analysis of a Single-Centre Experience

Applied Health Economics and Health Policy
Thathya V AriyaratneChristopher M Reid

Abstract

There are limited economic evaluations comparing coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) for multi-vessel coronary artery disease (MVCAD) in contemporary, routine clinical practice. The aim was to perform a cost-effectiveness analysis comparing CABG and PCI in patients with MVCAD, from the perspective of the Australian public hospital payer, using observational data sources. Clinical data from the Melbourne Interventional Group (MIG) and the Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) registries were analysed for 1022 CABG (treatment) and 978 PCI (comparator) procedures performed between June 2009 and December 2013. Clinical records were linked to same-hospital admissions and national death index (NDI) data. The incremental cost-effectiveness ratios (ICERs) per major adverse cardiac and cerebrovascular event (MACCE) avoided were evaluated. The propensity score bin bootstrap (PSBB) approach was used to validate base-case results. At mean follow-up of 2.7 years, CABG compared with PCI was associated with increased costs and greater all-cause mortality, but a significantly lower rate of MACCE. An ICER of $55,255 (Australian dollars)/MACCE avoided was obs...Continue Reading

References

Jan 1, 1995·International Journal of Technology Assessment in Health Care
Apr 1, 1993·Medical Decision Making : an International Journal of the Society for Medical Decision Making·D G FrybackP A Martin
Mar 3, 2004·Circulation·Victor M G LegrandUNKNOWN Arterial Revascularization Therapy Study (ARTS) Investigators
Feb 3, 2009·The American Journal of Medicine·Stuart L Silverman
May 5, 2011·JAMA : the Journal of the American Medical Association·Andrew J EpsteinPeter W Groeneveld
Oct 5, 2011·The Annals of Thoracic Surgery·Michael J MackA Pieter Kappetein
Jan 19, 2012·Circulation. Cardiovascular Quality and Outcomes·J Matthew BrennanUNKNOWN Duke Clinical Research Institute DEcIDE Team
Nov 6, 2012·The New England Journal of Medicine·Michael E FarkouhUNKNOWN FREEDOM Trial Investigators
Feb 23, 2013·Journal of the American College of Cardiology·Masoor KamaleshUNKNOWN VA CARDS Investigators
Feb 14, 2014·International Journal of Cardiology·Hariharan SugumarUNKNOWN Australia and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) & Melbourne Interventional Group (MIG)
Aug 12, 2014·The Annals of Thoracic Surgery·Ruben L OsnabruggeJeffrey B Rich
Jan 13, 2015·Journal of the American College of Cardiology·Zugui ZhangWilliam S Weintraub
Mar 18, 2015·Heart, Lung & Circulation·Akshat SaxenaPaul G Bannon

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Citations

Feb 16, 2020·International Journal of Environmental Research and Public Health·Elizabeth Parody-RúaIgnacio Aznar-Lou
Apr 23, 2021·Health Research Policy and Systems·Mitchell N SarkiesChris Reid

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