The regenerative potential of oxytalan fibers. An experimental study in the monkey

Journal of Clinical Periodontology
A SculeanN Lioubavina

Abstract

Although a number of studies have described the oxytalan fibers as being a natural component of the periodontal ligament, little information exists about the regenerative potential of these connective tissue fibers. The aim of the present study was to examine whether oxytalan fibers have the capacity to reform after regenerative periodontal therapy. Intrabony defects were produced surgically at the mesial aspects of teeth 37, 35, 45, 47 and at the distal aspects of teeth 11, 21, 31, 41 in one monkey (Macaca fascicularis). After 3 months, the defects were exposed using a full-thickness flap procedure. The root surfaces were debrided and subsequently PDGF-growth factors were placed in the defects. 4 of the 8 sites were covered with a bioresorbable membrane before closure of the wound. Post-surgically, antibiotics were given systemically for 1 week, and tooth cleaning was carried out 1x a week during the entire experimental period. After 5 months, the animal was sacrificed and the oral tissues were fixed by perfusion with 10% buffered formalin. Specimens containing the defects and surrounding tissues were dissected free and histological sections were cut in the mesio-distal direction, parallel to the long axes of the teeth. The se...Continue Reading

References

Oct 1, 1977·Journal of Morphology·W J Sampson, M R Sims
Jul 1, 1976·American Journal of Orthodontics·M R Sims
Jul 1, 1992·Journal of Periodontal Research·R B Johnson, S P Pylypas
Sep 1, 1989·Journal of Clinical Periodontology·S E LynchH N Antoniades
Jul 1, 1986·Journal of Clinical Periodontology·J GottlowJ Wennström
Jan 1, 1973·Journal of Oral Pathology·J H SheetzA J Narkates
Jan 1, 1974·Journal of Oral Pathology·H M FullmerA J Narkates
Jul 1, 1973·Journal of Dental Research·M R Sims
Jun 1, 1968·American Journal of Orthodontics·J G Edwards
Jan 1, 1966·The Journal of Cell Biology·G G Carmichael, H M Fullmer
Sep 1, 1984·Journal of Clinical Periodontology·J GottlowJ Lindhe
Jul 1, 1982·Journal of Clinical Periodontology·S NymanH Rylander
Mar 1, 1980·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·I E Jonas, U N Riede
Feb 1, 1993·Periodontology 2000·J G Caton, G Greenstein
Nov 1, 1958·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·H M FULLMER, R D LILLIE
May 1, 1959·Journal of Dental Research·H M FULLMER
Jul 1, 1960·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·H M FULLMER

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Citations

Jan 7, 2005·Clinical Oral Investigations·A SculeanM Brecx
Nov 6, 2009·Journal of Dental Research·G PellegriniW V Giannobile
Dec 20, 2014·Journal of Periodontal Research·M Kira-TatsuokaY Sawa
Jul 13, 2012·Archives of Oral Biology·Hardus StrydomJohannes W Von den Hoff
Jun 18, 2010·The Open Dentistry Journal·Xavier StruillouPierre Layrolle

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