PMID: 1883834Aug 23, 1991

The regulation and nature of the cyanide-resistant alternative oxidase of plant mitochondria

Biochimica Et Biophysica Acta
A L Moore, J N Siedow


In addition to possessing multiple NAD(P)H dehydrogenases, most plant mitochondria contain a cyanide- and antimycin-insensitive alternative terminal oxidase. Although the general characteristics of this terminal oxidase have been known for a considerable number of years, the mechanism by which it is regulated is unclear and until recently there has been relatively little information on its exact nature. In the past 5 years, however, the application of molecular and novel voltametric techniques has advanced our understanding of this oxidase considerably. In this article, we review briefly current understanding on the structure and function of the multiple NADH dehydrogenases and consider, in detail, the nature and regulation of the alternative oxidase. We derive a kinetic model for electron transfer through the ubiquinone pool based on a proposed model for the reduction of the oxidase by quinol and show how this can account for deviations from Q-pool behaviour. We review information on the attempts to isolate and characterise the oxidase and finally consider the molecular aspects of the expression of the alternative oxidase.


Dec 1, 1979·Canadian Journal of Biochemistry·G P Arron, G E Edwards
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Apr 17, 1978·European Journal of Biochemistry·J C de Troostembergh, E J Nyns
May 1, 1978·Archives of Biochemistry and Biophysics·P R Rich, W D Bonner
Aug 7, 1978·Biochimica Et Biophysica Acta·P R RichW D Bonner
Feb 1, 1979·Biochemical Society Transactions·J M Palmer
Mar 1, 1978·Archives of Biochemistry and Biophysics·A L MooreP R Rich
Sep 27, 1976·Biochimica Et Biophysica Acta·G C Hill
Aug 9, 1976·Biochemical and Biophysical Research Communications·P R RichA L Moore
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Mar 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·D M Rhoads, Lee McIntosh
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Nov 23, 1989·Biochimica Et Biophysica Acta·M P Murphy
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Apr 8, 1985·Biochimica Et Biophysica Acta·C I Ragan, I R Cottingham
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Nov 30, 1982·Biochemical and Biophysical Research Communications·A L Moore, K E Akerman
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Aug 1, 1993·Journal of Bioenergetics and Biomembranes·I M MøllerK M Fredlund
Aug 1, 1995·Journal of Bioenergetics and Biomembranes·A L MooreJ N Siedow
Aug 1, 1995·Journal of Bioenergetics and Biomembranes·D A Day, J T Wiskich
Aug 1, 1995·Journal of Bioenergetics and Biomembranes·C A Conley, M R Hanson
May 11, 2011·Journal of Bioenergetics and Biomembranes·Sergio Guerrero-CastilloSalvador Uribe-Carvajal
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Apr 1, 1995·Plant Physiology·J WhelanD A Day
Jan 1, 1996·Plant Physiology·C HiserLee McIntosh
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Apr 29, 2008·Biochimica Et Biophysica Acta·Anneke M WagnerAnthony L Moore
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Jan 29, 2011·Journal of Bioenergetics and Biomembranes·Vicente de Paulo MartinsSérgio Akira Uyemura
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Nov 7, 1998·The Journal of Biological Chemistry·M S AlburyA L Moore
Jul 18, 2017·Journal of Chemical Ecology·Érica Marusa Pergo CoelhoEmy Luiza Ishii-Iwamoto

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