The Regulation of Bacterial Biofilm Formation by cAMP-CRP: A Mini-Review

Frontiers in Microbiology
Cong LiuWeijie Liu

Abstract

Biofilms are communities of microorganisms that live in a self-produced extracellular matrix in order to survive in hostile environments. Second messengers, such as c-di-GMP and cAMP, participate in the regulation of biofilm formation. c-di-GMP is a major molecule that is involved in modulating the bacterial transition between a planktonic lifestyle and biofilm formation. Aside from regulating carbon catabolism repression in most bacteria, cAMP has also been found to mediate biofilm formation in many bacteria. Although the underlying mechanisms of biofilm formation mediated by cAMP-CRP have been well-investigated in several bacteria, the regulatory pathways of cAMP-CRP are still poorly understood compared to those of c-di-GMP. Moreover, some bacteria appear to form biofilm in response to changes in carbon source type or concentration. However, the relationship between the carbon metabolisms and biofilm formation remains unclear. This mini-review provides an overview of the cAMP-CRP-regulated pathways involved in biofilm formation in some bacteria. This information will benefit future investigations of the underlying mechanisms that connect between biofilm formation with nutrient metabolism, as well as the cross-regulation betwe...Continue Reading

References

Dec 11, 1999·Nucleic Acids Research·K E Rudd
May 25, 2002·Journal of Bacteriology·Debra W JacksonTony Romeo
Jun 8, 2002·FEMS Microbiology Letters·F Paola Corona-Izquierdo, Jorge Membrillo-Hernández
May 20, 2004·Journal of Bacteriology·Guillermo GossetMilton H Saier
Aug 9, 2005·Applied and Environmental Microbiology·Isabel Aranda-OlmedoSilvia Marqués
Jan 13, 2006·The Journal of Biological Chemistry·Young-Ha ParkAlan Peterkofsky
Jan 20, 2006·Molecular Microbiology·Arne Rietsch, John J Mekalanos
May 18, 2006·Annual Review of Microbiology·Michelle M Barnhart, Matthew R Chapman
Dec 13, 2006·Microbiology and Molecular Biology Reviews : MMBR·Josef DeutscherPieter W Postma
May 17, 2008·Nature Reviews. Microbiology·Fabienne F V Chevance, Kelly T Hughes
Oct 6, 2009·Journal of Bacteriology·Takayuki Endoh, Joanne N Engel
Jan 6, 2011·Proceedings of the National Academy of Sciences of the United States of America·Li XieXiao-Lun Wu
Jun 7, 2011·Annual Review of Microbiology·Aurelia BattestiSusan Gottesman
Aug 13, 2011·Frontiers in Microbiology·Manisha R DiazTimothy L Yahr
Sep 20, 2011·Journal of Bacteriology·Disha SrivastavaChristopher M Waters
Mar 14, 2013·FEMS Microbiology Reviews·Sarah B Guttenplan, Daniel B Kearns
Aug 8, 2013·PloS One·Eric J KalivodaRobert M Q Shanks
Jun 5, 2014·Trends in Microbiology·Robert Belas
Jan 28, 2015·Journal of Bacteriology·David Zamorano-SánchezFitnat H Yildiz
Jun 5, 2015·Proceedings of the National Academy of Sciences of the United States of America·Alexandre PersatZemer Gitai
Jun 25, 2015·Microbiology Spectrum·Dae-Gon Ha, George A O'Toole
Jul 15, 2015·Journal of Molecular Microbiology and Biotechnology·Sarah L SutrinaNikolai Holder
Dec 30, 2015·Proceedings of the National Academy of Sciences of the United States of America·Bruno Y MatsuyamaMarcos V A S Navarro

❮ Previous
Next ❯

Citations

Dec 29, 2020·Environmental Pollution·Huizhong LiuQingshan Shi
Apr 27, 2021·Frontiers in Microbiology·Fufeng JiangQingping Wu
Aug 10, 2021·Frontiers in Cellular and Infection Microbiology·Erin M VasicekJohn S Gunn
Dec 24, 2021·Critical Reviews in Biochemistry and Molecular Biology·Kumari Uma MahtoSurajit Das
Jan 14, 2022·ACS Synthetic Biology·Purnendu BhowmikSantanu Datta

❮ Previous
Next ❯

Methods Mentioned

BETA
phosphotransferase
GTPase

Related Concepts

Related Feeds

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.

Biofilms

Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.

Related Papers

Microbiology Spectrum
Tim Tolker-Nielsen
Bioscience, Biotechnology, and Biochemistry
Masanori ToyofukuNobuhiko Nomura
Applied and Environmental Microbiology
Suran KimJoon-Hee Lee
© 2022 Meta ULC. All rights reserved