PMID: 375022Mar 9, 1979Paper

The regulation of hexokinase and phosphoglucomutase activity in Aspergillus nidulans

Molecular & General Genetics : MGG
N S Dunn-Coleman, J A Pateman

Abstract

The levels of glucose-6-phosphate and 6-phosphogluconate dehydrogenase in wildtype cells of Aspergillus nidulans varied with the carbon and nitrogen source. In general, hexokinase activity did not vary with carbon or nitrogen source. The ammonium derepressed mutant amrA1 had only 50% of the wildtype level of hexokinase. Phosphoglucomutase activity was low in wildtype cells grown with nitrate, but high in cells grown with ammonium when glucose was the carbon source. A non-inducible mutant, nirA-1, in the regulatory gene for nitrate reductase, had high phosphoglucomutase activity when grown with nitrate or ammonium. A constitutive mutant nirAc1, in the regulatory gene for nitrate reductase had low phosphoglucomutase activity when grown with nitrate or ammonium. The mutants nir-1 and nirAc1 are recessive and semi-dominant respectively for abnormal phosphoglucomutase activity.

References

Apr 29, 1977·Molecular & General Genetics : MGG·N S Dunn-Coleman, J A Pateman
Jan 1, 1975·Canadian Journal of Microbiology·O Hankinson, D J Cove
Oct 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·S Brody, E L Tatum
Jul 1, 1967·The Biochemical Journal·J A PatemanD J Cove
Mar 1, 1974·Journal of Bacteriology·O Hankinson
Jan 1, 1971·Molecular & General Genetics : MGG·M V Elorza, H N Arst
Mar 1, 1969·Journal of Bacteriology·D J Cove, J A Pateman
Sep 16, 1967·Nature·J A Pateman, D J Cove
Jan 1, 1953·Advances in Genetics·G PONTECORVOA W J BUFTON

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Citations

Sep 1, 1982·Critical Reviews in Toxicology·I Chanarin
Apr 1, 1982·Journal of Child Psychology and Psychiatry, and Allied Disciplines·C Kendrick, J Dunn
Jul 21, 2007·The EMBO Journal·Richard A WilsonNicholas J Talbot

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