Mar 1, 1976

The regulation of physiological changes during mammalian aging

The Quarterly Review of Biology
C E Finch


Much evidence suggests that intrinsic molecular or cellular aging mechanisms need not be invoked to explain most age-related cellular changes and pathologcical conditions. Analysis of a widely scattered literature indicates that hormones and neural factors regulate a great number of cellular aging phenomena of mammals. It is proposed that age-related changes after maturation result from an extension of the neural and endocrine mechanisms that control earlier development and that produce a regulatory cascade of changing neural, endocrine, and target-tissue interactions.

  • References
  • Citations95


  • We're still populating references for this paper, please check back later.

Mentioned in this Paper

Cell Aging
Endocrine Glands
Biologic Development
Pigments, Biological
Endocrine System
Etat Marbre

About this Paper

Related Feeds

Brain Aging

Here is the latest research on intrinsic and extrinsic factors, as well as pathways and mechanisms that underlie aging in the central nervous system.