PMID: 18720853Aug 30, 2008Paper

The regulation of sigmaB activity and its role in some gram-positive food-borne pathogens--a review

Wei sheng wu xue bao = Acta microbiologica Sinica
Yingying FengQingchun Zhou

Abstract

The alternative sigma factor sigmaB modulates the stress response of several Gram-positive bacteria. Not only does sigmaB play a prominent role in sporulation in the Gram-positive model organism Bacillus subtilis, but it also contributes both directly and indirectly to bacterial virulence in the food-borne human pathogens Bacillus cereus, Listeria monocytogenes and Staphylococcus aureus. As sigmaB has been shown to regulate expression of both virulence and virulence-associated genes, it indicates that sigmaB is a key player in pathogen ecophysiology.

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