Apr 5, 2020

Thermal adaptation rather than demographic history drives genetic structure inferred by copy number variants in a marine fish

BioRxiv : the Preprint Server for Biology
Hugo CayuelaL. Bernatchez

Abstract

Increasing evidence shows that structural variants represent an overlooked aspect of genetic variation with consequential evolutionary roles. Among those, copy number variants (CNVs), including duplicated genomic region and transposable elements (TEs) may contribute to local adaptation and/or reproductive isolation among divergent populations. Those mechanisms suppose that CNVs could be important drivers of population genetic structure, whose study is generally restricted to the use of SNPs. Taking advantage of recent developments allowing CNV analysis from RAD-seq data, we investigated how variation in fitness-related traits, local thermal conditions and demographic history are associated with CNVs, and how subsequent copy number variation drives population genetic structure in a marine fish, the capelin (Mallotus villosus). We collected 1536 DNA samples from 35 sampling sites in the north Atlantic Ocean and identified 6620 CNVs. We found associations between CNVs and the gonadosomatic index, suggesting that duplicated regions could affect female fitness by modulating oocyte production. We also detected 105 CNV candidates associated with water temperature, among which 20% corresponded to genomic regions located within the sequ...Continue Reading

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Fertility
NGFRAP1 protein, human
Genes
Saccharomyces cerevisiae allergenic extract
Infertility Study
Gene Deletion Abnormality
Gene Deletion
Genes, Regulator
Deletion Mutation
Observation - Diagnostic Procedure

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.

Related Papers

Current Genetics
Stephanie Lauer, David Gresham
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik
Agnieszka ŻmieńkoMarek Figlerowicz
© 2020 Meta ULC. All rights reserved