PMID: 9444647Jan 28, 1998Paper

The relation between various histological types of lung cancer and the number of years since cessation of smoking

Lung Cancer : Journal of the International Association for the Study of Lung Cancer
H PohlabelnK M Müller

Abstract

We studied the relation between various histological types of lung cancer and the number of years of cessation from smoking using data from a recently completed case-control study in Northern Germany. In this context we wanted to answer the question whether smoking cessation is a specific symptom of small cell lung cancer. Defining current smokers as the reference group the odds ratios decreased with years of cessation. Based on the analysis of all male cases and controls in our study, former smokers who stopped smoking 6-10 years ago had an odds ratio of 0.97 (95% confidence interval (C.I.) = 0.65-1.45), ex-smokers with 11-20 years of smoking cessation had a reduced risk of 0.55 (95% C.I. = 0.38-0.79), and for more than 20 years of cessation we found an odds ratio of 0.25 (95% C.I. = 0.16-0.40). Moreover, these calculations are also presented for the major groups of histological types of lung cancer. Our data show that there is no evidence for the presumption that cases with small cell lung cancer stop smoking earlier than cases with other histological types: in no other histological category we found such a big part of current smokers.

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Citations

Aug 16, 2003·Progress in Cardiovascular Diseases·James Lightwood
Feb 13, 2001·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·S A Khuder
Mar 8, 2007·Evidence-based Complementary and Alternative Medicine : ECAM·Wenbin LiangAndy H Lee
Jul 13, 2011·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Lap Ah TseKai Shing Yu
Jan 25, 2011·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Barbara G CamplingMiu Lam
Oct 26, 2000·Japanese Journal of Cancer Research : Gann·H SodaS Kohno
May 31, 2016·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Guilherme CostaCarlos Gil Ferreira

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