The relation of falls to fatigue, depression and daytime sleepiness in Parkinson's disease.

European Neurology
M S BryantE J Protas

Abstract

To characterize non-motor symptoms in individuals with Parkinson's disease (PD) who experience falls compared to those who do not fall. Fifty-four individuals with PD were studied. Thirty-six were fallers and 18 were non-fallers. Fatigue was assessed by the Iowa Fatigue Scale. Excessive daytime sleepiness was assessed by the Epworth Sleepiness Scale, and depressive symptomatology was assessed by the short-form Center for Epidemiologic Studies Depression Scale. Compared to non-fallers, fallers had more severe disability, greater general physical fatigue (p = 0.024), lower energy levels (p = 0.042) and less productivity (p = 0.007). Fallers had more depressive symptomatology than the non-fallers (p = 0.01). Excessive daytime sleepiness was not different between the two groups (p = 0.695). Individuals with PD who fell had more severe motor and non-motor symptoms than those who did not fall. These non-motor symptoms included physical fatigue, energy, productivity and depressive symptomatology.

References

Jan 1, 1990·The Journal of Nervous and Mental Disease·S E StarksteinR G Robinson
Apr 1, 1989·Clinical Neuropharmacology·W C KollerR Hassanein
Jan 1, 1985·Clinical Neuropharmacology·C J BulpittJ L Reid
Jan 1, 1967·Medicina Et Pharmacologia Experimentalis. International Journal of Experimental Medicine·B DjahanguiriA Firouzabadi
Jan 1, 1993·Journal of Neural Transmission. General Section·A S Brown, S Gershon
Sep 20, 2000·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·P Gray, K Hildebrand
May 23, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·B H WoodR W Walker
Nov 28, 2002·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·K Herlofson, J P Larsen
Jan 25, 2003·Acta Neurologica Scandinavica·K Herlofson, J P Larsen
Jun 5, 2003·Journal of Psychosomatic Research·Arthur HartzDavid Watson
Sep 21, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·L M AllcockD J Burn
Sep 24, 2005·The Journal of Neuropsychiatry and Clinical Neurosciences·Connie VeazeyMark E Kunik
Apr 20, 2006·Parkinsonism & Related Disorders·Emilia MartignoniGiuseppe Nappi
Jun 22, 2006·Journal of Neurology, Neurosurgery, and Psychiatry·M B van IerselM G M Olde Rikkert
Jun 27, 2006·Journal of the Neurological Sciences·Anette Schrag
Sep 28, 2007·Brain : a Journal of Neurology·Thomas C ThannickalJerome M Siegel
Dec 7, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Galit Yogev-SeligmannNir Giladi
May 20, 2008·Parkinsonism & Related Disorders·L M AllcockD J Burn
Jan 8, 2009·Annals of Neurology·Tanya Simuni, Kapil Sethi
Apr 21, 2009·Lancet Neurology·K Ray Chaudhuri, Anthony H V Schapira
Mar 17, 2010·Neurology·T A ZesiewiczUNKNOWN Quality Standards Subcommittee of the American Academy of Neurology
May 4, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·K Ray ChaudhuriPablo Martinez-Martin
May 25, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·P R Castillo
May 25, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·P O ValkoC R Baumann
Jul 1, 2010·Acta Neurologica Scandinavica. Supplementum·A G Beiske, E Svensson
Oct 27, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Antoine G BeiskeElisabeth Svensson
Jan 5, 2011·Neuro-degenerative Diseases·Claudio L Bassetti
Feb 18, 2011·CNS Drugs·Bettina KnieK Ray Chaudhuri
May 31, 2011·Journal of the Neurological Sciences·Pablo Martinez-Martin
Aug 2, 2011·Internal Medicine·Hideto Miwa, Takako Miwa

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Citations

Jan 29, 2013·Journal of Neural Transmission·Cristian Falup-Pecurariu
Oct 11, 2013·Clinical Nurse Specialist CNS·Huey-Ming Tzeng, Chang-Yi Yin
Dec 31, 2015·Movement Disorders : Official Journal of the Movement Disorder Society·Gretchen O ReynoldsAlice Cronin-Golomb
May 9, 2015·Parkinsonism & Related Disorders·Elan D Louis, Duarte G Machado
Aug 25, 2010·Toxicon : Official Journal of the International Society on Toxinology·Nora G MontoyaJosé I Carreto
Jun 11, 2015·NPJ Parkinson's Disease·Anette SchragDavid A Gallagher
Dec 12, 2019·Arquivos de neuro-psiquiatria·Alonso Alvarado-BolañosMayela Rodríguez-Violante
Feb 18, 2021·Multiple Sclerosis and Related Disorders·Jenna N CohenFrederick W Foley
Feb 26, 2020·Clinical Parkinsonism & Related Disorders·Herb KarpatkinDavid Schroeder

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