The relation of optic nerve sheath diameter (ONSD) and intracranial pressure (ICP) in pediatric neurosurgery practice - Part II: Influence of wakefulness, method of ICP measurement, intra-individual ONSD-ICP correlation and changes after therapy.

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
Susanne R KerscherMartin U Schuhmann

Abstract

Previous studies correlating ultrasound (US)-based optic nerve sheath diameter (ONSD) and intracranial pressure (ICP) in children were performed under general anesthesia. To apply ONSD in daily clinical routine, it is necessary to investigate patients awake. It is furthermore essential for ICP-assessment with ONSD to know if ONSD-ICP correlation varies within individuals. In this study, we report on the influence of wakefulness, method of ICP measurement, intraindividual correlations, and dynamic changes of ONSD and ICP after ICP decreasing therapy. The overall study included 72 children with a median age of 5.2 years. US ONSD determination was performed immediately prior to invasive ICP measurement, and the mean binocular ONSD was compared to ICP. In 10 children, a minimum of 3 ONSD/ICP measurements were performed to investigate a correlation within subjects. In 30 children, measurements were performed before and after therapy. Twenty-eight children were investigated awake with an excellent correlation of ONSD and ICP (r = 0.802, p < 0.01). In 10 children, at least three simultaneous ONSD and ICP measurements were performed. The intraindividual correlations were excellent (r = 0.795-1.0) however with strongly differing individ...Continue Reading

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Sep 24, 2016·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Llewellyn C PadayachyA Graham Fieggen
Sep 24, 2016·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Llewellyn C PadayachyA Graham Fieggen
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Jul 1, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Susanne R KerscherMartin U Schuhmann

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Citations

Apr 23, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Sandra F DiasMartin U Schuhmann

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