The relation of peripheral arterial disease to leg force, gait speed, and functional dependence among older adults

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Hsu-Ko Kuo, Yau-Hua Yu

Abstract

Atherosclerotic peripheral arterial disease (PAD), common among older adults, is associated with poor low-extremity functioning. In considering functional status, varying domains exist, including activities of daily living (ADL), instrumental activities of daily living (IADL), low-extremity mobility (LEM), and leisure and/or social activities (LSA). However, little is known about how PAD is related to functional status beyond low-extremity functioning. A total of 1798 participants 60 years old or older was selected from the population-based National Health and Nutrition Examination Survey 1999-2002 in the United States. ADL, IADL, LSA, LEM, and general physical activities (GPA) were obtained by self-report. Peak leg force was obtained from an isokinetic dynamometer. Habitual gait speed was obtained from a 20-foot timed walk. PAD was defined as an ankle-brachial blood pressure index <0.9 in either leg. After multivariable adjustment, the odds ratios (ORs) for dependence in IADL, LSA, and LEM comparing participants with PAD to those without were 1.60 (95% confidence interval [CI], 1.11-2.29), 1.63 (95% CI, 1.08-2.44), and 2.29 (95% CI, 1.64-3.18), respectively. Additional adjustment of peak leg force and/or habitual gait speed di...Continue Reading

References

Jan 1, 1994·Social Science & Medicine·L M Verbrugge, A M Jette
Jun 1, 1997·Medical Care·A M Jette
Mar 4, 1998·Arteriosclerosis, Thrombosis, and Vascular Biology·W T MeijerD E Grobbee
Nov 11, 1998·Journal of the American Geriatrics Society·M M McDermottP Greenland
Apr 16, 1999·Journal of General Internal Medicine·M M McDermottP Greenland
May 25, 2002·Journal of the American Geriatrics Society·Mary McGrae McDermottJack M Guralnik
Jun 19, 2002·Annals of Internal Medicine·Mary McGrae McDermottElizabeth Clark
Jul 29, 2004·JAMA : the Journal of the American Medical Association·Mary McGrae McDermottElizabeth Clark
Oct 3, 2006·Journal of Vascular Surgery·Susan A SchererJudith G Regensteiner

❮ Previous
Next ❯

Citations

Sep 24, 2013·International Journal of Behavioral Medicine·Anna-Karin WelmerChengxuan Qiu
Jan 16, 2016·Rehabilitation Research and Practice·Sara A MyersJason M Johanning
Mar 12, 2011·Journal of the American Geriatrics Society·Yau-Hua YuHsu-Ko Kuo
Jul 31, 2010·Journal of Vascular Surgery·Panagiotis KoutakisIraklis I Pipinos
Oct 20, 2009·Journal of Vascular Surgery·Panagiotis KoutakisJason M Johanning
Oct 14, 2010·American Journal of Hypertension·Nora L WatsonUNKNOWN Health ABC Study
Nov 26, 2009·The Journal of International Medical Research·Andrej Kravos, K Bubnic-Sotosek
Nov 14, 2017·Journal of the American Geriatrics Society·Ali EzzatiCarol A Derby
Nov 11, 2017·Journal of the American Geriatrics Society·Emerald G HeilandAnna-Karin Welmer
Jul 11, 2020·Journal of Cachexia, Sarcopenia and Muscle·Mégane PizzimentiBernard Geny
Oct 25, 2017·Journal of Strength and Conditioning Research·David J Fonseca AlvesClaudio Córdova
Feb 20, 2019·Environmental Science and Pollution Research International·Yuan-Yuei ChenWei-Liang Chen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.