The relation of serum levels of antioxidant vitamins C and E, retinol and carotenoids with pulmonary function in the general population

American Journal of Respiratory and Critical Care Medicine
H J SchünemannM Trevisan

Abstract

Reduced pulmonary function is an important predictor of mortality in the general population, and antioxidant vitamins are thought to positively influence pulmonary function. Vitamin C, vitamin E, retinol, and carotenoids are powerful antioxidants but information about the joint relation of serum levels of these antioxidants to pulmonary function is limited. We analyzed the association of FEV(1) and FVC with serum vitamins C and E, retinol, and carotenoids (beta-cryptoxanthin, lutein/zeaxanthin, beta-carotene, and lycopene) in a cross-sectional study. The analysis was carried out in a sample of 1,616 randomly selected residents of Western New York, USA, age 35 to 79 yr and free of respiratory disease. Lung function was adjusted for height, age, sex, and race and expressed as percentage of predicted normal FEV(1) (FEV(1)%) and FVC (FVC%). Participants in the lowest quartile of each of the serum antioxidants had consistently lower FEV(1)% and FVC% than those in higher quartiles. Multiple linear regression analysis revealed significant associations of vitamin C, vitamin E, beta-cryptoxanthin, lutein/zeaxanthin, beta-carotene, and retinol with FEV(1)% when these variables were investigated individually after adjustment for other cov...Continue Reading

References

May 13, 1976·The New England Journal of Medicine·G D FriedmanA B Siegelaub
Aug 1, 1992·The American Journal of Clinical Nutrition·D W Nierenberg, S L Nann
May 1, 1991·The American Review of Respiratory Disease·C FretteF Kauffmann
Jul 1, 1990·American Journal of Epidemiology·A MorabiaM S Tockman
Aug 1, 1989·The American Review of Respiratory Disease·J E Heffner, J E Repine
Nov 1, 1989·The American Review of Respiratory Disease·A MorabiaE Chee
Jan 1, 1985·Annual Review of Nutrition·P B McCay
Dec 1, 1995·The American Journal of Clinical Nutrition·H Sies, W Stahl
May 1, 1995·American Journal of Respiratory and Critical Care Medicine·P Burney
May 1, 1995·American Journal of Respiratory and Critical Care Medicine·J R BrittonS T Weiss
Oct 1, 1994·American Journal of Respiratory and Critical Care Medicine·E ShaharM Szklo
May 28, 1993·Annals of the New York Academy of Sciences·C E CrossB Frei
Jan 1, 1996·The Journal of Nutrition·W E BradyM Stacewicz-Sapuntzakis
May 2, 1996·The New England Journal of Medicine·G S OmennS Hammar
Nov 1, 1996·American Journal of Respiratory and Critical Care Medicine·C A RedlichW S Blaner
Mar 1, 1997·American Journal of Respiratory and Critical Care Medicine·P ChuwersJ R Balmes
Aug 1, 1997·American Journal of Respiratory and Critical Care Medicine·J E RepineI Lankhorst
Dec 24, 1997·American Journal of Epidemiology·H J SchünemannM Trevisan
Sep 30, 1998·American Journal of Epidemiology·G HuP A Cassano
Apr 28, 1999·Free Radical Biology & Medicine·V P PalaceP K Singal
Jul 3, 1999·Nutrition Reviews·D A CooperJ C Peters
Nov 11, 1999·American Journal of Respiratory and Critical Care Medicine·W Macnee, I Rahman
Nov 11, 1999·European Journal of Clinical Nutrition·L GrievinkD Kromhout
Mar 11, 2000·American Journal of Respiratory and Critical Care Medicine·L GrievinkF J Kok

❮ Previous
Next ❯

Citations

Jan 27, 2005·Journal of Behavioral Medicine·Yih-Ing HserM Douglas Anglin
Jan 14, 2003·Sleep & Breathing = Schlaf & Atmung·Holger J SchünemannMaurizio Trevisan
Feb 4, 2003·Current Allergy and Asthma Reports·Sarah I DennyBarrie M Margetts
Jun 19, 2013·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Jennifer F Lai, Adrian A Franke
Mar 14, 2003·Free Radical Biology & Medicine·Florian GuthmannBernd Rüstow
Sep 30, 2005·Journal of the American College of Nutrition·Aasma ShaukatHolger J Schünemann
Nov 3, 2005·Journal of Toxicology and Environmental Health. Part a·Janneke G F HogervorstConstant P van Schayck
Mar 11, 2010·Antioxidants & Redox Signaling·Lisa G WoodManohar L Garg
Apr 18, 2009·American Journal of Epidemiology·Jennifer A NettletonMatthew B Schabath
Nov 11, 2010·Journal of Occupational and Environmental Medicine·Luenda E CharlesHeather M Ochs-Balcom
Mar 5, 2002·American Journal of Respiratory and Critical Care Medicine·Martin J Tobin
May 11, 2005·American Journal of Respiratory and Critical Care Medicine·Suzy A A ComhairSerpil C Erzurum
Aug 31, 2010·American Journal of Respiratory and Critical Care Medicine·Mark D EisnerUNKNOWN Committee on Nonsmoking COPD, Environmental and Occupational Health Assembly
May 7, 2002·American Journal of Respiratory and Critical Care Medicine·Tricia M McKeeverSarah A Lewis
Dec 10, 2002·American Journal of Respiratory and Critical Care Medicine·Ingrid KolleckBernd Rüstow
Dec 8, 2010·Respiratory Research·Ioanna G Tsiligianni, Thys van der Molen
Oct 1, 2008·Respiratory Research·Tricia M McKeeverJohn Britton
Jan 10, 2013·PloS One·Tze Pin NgWan Cheng Tan
Nov 9, 2011·Sports Medicine·Tina-Tinkara Peternelj, Jeff S Coombes
May 14, 2009·Journal of Nutritional Science and Vitaminology·Handan MertNihat Mert
Nov 5, 2013·Nutrients·Hiam Abdala-ValenciaJoan M Cook-Mills
Aug 21, 2013·Psychosomatic Medicine·Heather M Ochs-BalcomHolger J Schünemann
Feb 23, 2013·Archives of Environmental & Occupational Health·Huey-Jen SuHsiu-Ling Chen
Aug 3, 2013·American Journal of Respiratory and Critical Care Medicine·Joan M Cook-MillsTina Hartert
Oct 16, 2014·The British Journal of Nutrition·Earl S FordJanet B Croft
Sep 2, 2014·International Immunopharmacology·Joan M Cook-Mills, Pedro C Avila
Apr 14, 2012·The Journal of Nutrition, Health & Aging·R D SembaL P Fried
Jan 24, 2015·Journal of Dietary Supplements·Catherine Ulbricht
Sep 14, 2007·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Dora Il'yasovaMarco Pahor
May 21, 2013·Translational Research : the Journal of Laboratory and Clinical Medicine·Corrine HansonStephen Rennard
Mar 20, 2012·Allergologia et immunopathologia·Javier Torres-BorregoAna Belén Molina-Terán
Dec 7, 2007·Pulmonary Pharmacology & Therapeutics·Robert ForonjyJeanine D'Armiento
May 20, 2015·European Journal of Applied Physiology·Leonie M ChenowethCraig A Harms
Jan 28, 2014·The Lancet. Respiratory Medicine·Yueh-Ying HanJuan C Celedón
Oct 22, 2010·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Scott D SagelKonstantinos A Papas

❮ Previous
Next ❯

Related Concepts

Related Feeds

American Thoracic Association Journals

Discover the latest respiratory research published by the journals from the American Thoracic Society.