The relation of vitamin D deficiency with puberty and insulin resistance in obese children and adolescents

Journal of Pediatric Endocrinology & Metabolism : JPEM
Muammer BuyukinanEylem Ulas Saz

Abstract

The prevalence of obesity among children and adolescents has been rapidly increasing in recent years. Obese individuals are at risk for vitamin D deficiency. The aim of this study was to investigate the relation of vitamin D deficiency with puberty and insulin resistance in obese children and adolescents. A total of 106 children and adolescents (48 prepubertal and 58 pubertal) between 8 and 16 years of age were included in the study. Fasting blood glucose, insulin, lipid profile, calcium, phosphorus, alkaline phosphatase, parathyroid hormone, 25-hydroxyvitamin D [25(OH)D] levels, as well as blood glucose and insulin concentrations at 120 min of oral glucose tolerance test were measured. Insulin resistance was calculated using the homeostasis model assessment. Daily vitamin D intake was questioned. Serum 25(OH)D level was normal in only 3.8%, insufficient in 34.0%, and deficient in 62.2% of the subjects. There was a statistically significant rate of 25(OH)D deficiency in the pubertal group compared with that in the prepubertal group. Those subjects with 25(OH)D deficiency were found to have greater insulin resistance. Vitamin D deficiency is common among obese children and adolescents. Low vitamin D levels in obese individuals m...Continue Reading

Citations

Jun 8, 2013·Nutrients·Luciana Nunes MoscaTamara Beres Lederer Goldberg
Apr 29, 2014·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·David Jiménez-PavónLuis A Moreno
Jan 1, 2013·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·E Palomo AtanceJ Giralt Muiña
Aug 13, 2015·International Journal of Obesity : Journal of the International Association for the Study of Obesity·G CedielR Uauy
Apr 22, 2015·Revista paulista de pediatria : orgão oficial da Sociedade de Pediatria de São Paulo·Kelly Aparecida da CunhaJuliana Farias de Novaes
Dec 10, 2014·Therapeutic Advances in Endocrinology and Metabolism·Catherine A PetersonAnthony M Belenchia
Feb 23, 2017·World Journal of Clinical Pediatrics·Motti Haimi, Richard Kremer
Sep 30, 2017·Global Pediatric Health·Valerie O'HaraKathrin Hastey
Dec 30, 2015·Journal of Korean Medical Science·Eun Jae ChangHye Ran Yang
Jun 9, 2015·Public Health Nutrition·Forough SakiMarzieh Bakhshayeshkaram
May 8, 2016·The British Journal of Nutrition·Lucinda J BlackTrevor A Mori
Mar 1, 2020·Journal of Pediatric Endocrinology & Metabolism : JPEM·Yunue Flores RuelasCarmen Alicia Sánchez Ramírez
Dec 16, 2016·Journal of Pediatric Endocrinology & Metabolism : JPEM·Tal GrunwaldFrancesco De Luca
Jul 28, 2016·Journal of Pediatric Endocrinology & Metabolism : JPEM·Derya TepeMurat Kizilgun
Mar 13, 2014·Journal of Pediatric Endocrinology & Metabolism : JPEM·Vytas P KaraliusRamon Durazo-Arvizu
Aug 26, 2014·Journal of Pediatric Endocrinology & Metabolism : JPEM·Sonsoles Gutiérrez MedinaLeandro Soriano-Guillén
Jun 9, 2015·Journal of Pediatric Endocrinology & Metabolism : JPEM·Anna S ChallaEkaterini C Siomou
Aug 9, 2019·International Journal of Obesity Supplements·Silvia MigliaccioUNKNOWN Obesity Programs of nutrition, Education, Research and Assessment (OPERA) Group
Dec 31, 2014·Paediatrics and International Child Health·Hassib NarchiAisha Al Dhaheri
Oct 16, 2015·The Journal of Clinical Endocrinology and Metabolism·Feitong WuQian Zhang
Dec 29, 2020·Nutrition Reviews·Kalliopi K GkouskouAristides G Eliopoulos

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