The relationship between age at onset and comorbidity in psychiatric disorders

The Journal of Nervous and Mental Disease
K L Kasch, D N Klein

Abstract

The Epidemiologic Catchment Area community sample data were analyzed to determine whether there is a general tendency for subjects with two or more disorders to have an earlier age of onset of the index disorder than subjects with only one disorder. DSM-III axis I disorders and antisocial personality were each used as index disorders in separate logistic regressions. The results show that an earlier age of onset is associated with greater comorbidity in major depression, with a similar trend for alcoholism. Schizophrenia and the phobias, however, showed significant results in the opposite direction. Overall, the results argue for specific rather than general effects of age of onset on comorbidity.

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Citations

Jun 22, 2001·Drug and Alcohol Dependence·S E Gilman, H D Abraham
Jul 6, 2000·European Psychiatry : the Journal of the Association of European Psychiatrists·P Batel
Apr 30, 1999·The Journal of Nervous and Mental Disease·T SatoS Hirano
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Aug 25, 2009·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Bellinda King-KallimanisRobert Kohn
Oct 3, 2013·Journal of Psychiatric Research·Lee TibiGideon E Anholt
Oct 21, 2016·Asia-Pacific Psychiatry : Official Journal of the Pacific Rim College of Psychiatrists·Yuan FengYu-Tao Xiang
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May 2, 2000·The British Journal of Psychiatry : the Journal of Mental Science·S PiniG Cassano

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