The Relationship Between Blue-Fundus Autofluorescence and Optical Coherence Tomography in Eyes With Lamellar Macular Holes

Investigative Ophthalmology & Visual Science
Roberto dell'OmoFerdinando Bottoni

Abstract

The purpose of this study was to evaluate the relationship between blue-fundus autofluorescence (B-FAF) and optical coherence tomography (OCT) in eyes with lamellar macular holes (LMHs). this was a multicenter, observational case series. Ninety-two eyes with LMH associated with the standard epiretinal membrane (ERM) or lamellar hole-associated epiretinal proliferation (LHEP) were evaluated. The eyes must also present an area of increased autofluorescence on B-FAF. The ERM-alone group and the LHEP group differed with respect to the following variables: logarithm of the minimum angle of resolution best-corrected visual acuity (0.13 ± 0.13 vs. 0.25 ± 0.17; P < 0.001), central foveal thickness (218.74 ± 52.4 μm vs. 187.28 ± 50.29 μm; P = 0.008), FAF diameter (400.78 ± 189.36 μm vs. 503.37 ± 214.25 μm; P = 0.014), outer plexiform layer (OPL) diameter (382.10 ± 157.34 μm vs. 550.79 ± 228.05 μm; P = 0.0001), and disruption of external limiting membrane and ellipsoid zone, which was noted in only 1 and 3 eyes with ERM alone, respectively, and in 18 and 23 eyes with LHEP, respectively (P < 0.0001 for both observations). No difference was found for diameters measured at the level of the inner limiting membrane and schisis/cavitation. In ...Continue Reading

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Citations

Sep 9, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Roberto dell'OmoFerdinando Bottoni
Oct 4, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ismael ChehaibouJean-Pierre Hubschman
Mar 19, 2019·Journal of Ophthalmology·Ferdinando Bottoni
Jul 11, 2020·International Journal of Retina and Vitreous·Andreas BringmannPeter Wiedemann
Feb 29, 2020·The British Journal of Ophthalmology·Jean Pierre HubschmanRamin Tadayoni
Jan 13, 2021·International Ophthalmology·Andreas BringmannPeter Wiedemann
Feb 20, 2021·Journal of Ophthalmology·Roberto dell'OmoCiro Costagliola
Jan 16, 2020·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Ferdinando BottoniGrazia Pertile

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