The Relationship between Cardiorespiratory Fitness and Montreal Cognitive Assessment Scores in Older Adults

Gerontology
Stephen W FarrellLaura F DeFina

Abstract

Relatively little is known regarding the association between objective measures of physical function such as cardiorespiratory fitness (CRF) and cognitive function tests in healthy older adults. To evaluate the relationship between CRF and cognitive function in adults aged 55 and older. Between 2008 and 2017, 4,931 men and women underwent a comprehensive preventive physical exam at the Cooper Clinic in Dallas, Texas. CRF was determined by duration of a maximal treadmill exercise test. Cognitive function was evaluated with the Montreal Cognitive Assessment (MoCA). In a multivariate model, adjusted odds ratios with 95% confidence intervals for MoCA scores < 26 (i.e., cognitive impairment) were determined by using CRF as both a continuous and a categorical variable. The mean age of the sample was 61.0 ± 6.0 years; mean maximal MET values were 10.0 ± 2.2. Mean MoCA scores were 26.9 ± 2.2; 23.4% of the sample had MoCA scores indicative of cognitive impairment. The odds ratio for cognitive impairment was 0.93 (0.88-0.97) per 1-MET increment in CRF. When examined as a categorical variable, and using the lowest CRF quintile as the referent, there was a significantly reduced likelihood for cognitive impairment across the remaining order...Continue Reading

References

Mar 20, 2001·Archives of Neurology·D LaurinK Rockwood
Apr 27, 2001·Medicine and Science in Sports and Exercise·P T Williams
Jan 5, 2005·The American Journal of Medicine·Jonathan MyersVictor Froelicher
Apr 9, 2005·Journal of the American Geriatrics Society·Ziad S NasreddineHoward Chertkow
May 21, 2009·JAMA : the Journal of the American Medical Association·Satoru KodamaHirohito Sone
Jan 13, 2010·Archives of Neurology·Laura D BakerSuzanne Craft
Sep 18, 2010·Journal of Alzheimer's Disease : JAD·Laura D BakerSuzanne Craft
Jan 25, 2011·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Walter A RoccaLon R White
Mar 13, 2012·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·UNKNOWN Alzheimer's Association
Feb 6, 2013·Annals of Internal Medicine·Laura F DefinaJarett D Berry
Dec 22, 2014·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Scott M HayesMieke Verfaellie
Nov 26, 2016·International Journal of Cardiology·Meghan K Edwards, Paul D Loprinzi

❮ Previous
Next ❯

Citations

Mar 21, 2019·International Journal of Environmental Research and Public Health·Su-Youn Cho, Hee-Tae Roh
Aug 29, 2021·Journal of Aging and Physical Activity·Tal GafniLaura F DeFina
Jan 3, 2020·Journal of Strength and Conditioning Research·Stephen W FarrellWilliam L Haskell

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.