The relationship between clinical and biochemical characteristics and quality of life in patients with polycystic ovary syndrome

Clinical Endocrinology
Mina AmiriFahimeh Ramezani Tehrani

Abstract

While has been well demonstrated that clinical characteristics of polycystic ovary syndrome (PCOS) are associated with an impaired quality of life (QoL) in patients, it is unclear that whether the biochemical aspects of PCOS can influence their QoL. We aimed to investigate the relationship between clinical and biochemical characteristics, and various domains of QoL in patients with PCOS. A cross-sectional study. We assessed the association between clinical and biochemical characteristics and QoL domains (psychosocial-emotional, fertility, sexual function, and obesity-menstrual) in a total of 211 women with PCOS using a specific health-related quality-of-life questionnaire for PCOS patients. Our findings showed positive significant association of QoL with age, and its negative significant associations with BMI, hirsutism and infertility (P < 0.05). We also found a negative association between FAI and total QoL (r = -0.14; P = 0.042) and domains of hirsutism (r = -0.14; P = 0.045) and obesity-menstrual (r = -0.23; P = 0.001). DHEAS was positively associated with the sexual function aspect of QoL (r = 0.20; P = 0.043). There were no significant associations between QoL and other hormonal parameters including LH to FSH ratio and to...Continue Reading

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Citations

Jan 24, 2020·The Journal of Clinical Endocrinology and Metabolism·Salla KarjulaTerhi T Piltonen
Jul 18, 2020·Health and Quality of Life Outcomes·María L Sánchez-FerrerAlberto M Torres-Cantero
Dec 12, 2020·Saudi Journal of Biological Sciences·Syed Mohammed Basheeruddin AsdaqMohammed Jaber Al-Yamani
Apr 22, 2021·Current Psychiatry Reports·Lindsay R StandevenLiisa Hantsoo
Jun 11, 2021·Frontiers in Physiology·Mohammed Altigani AbdallaThozhukat Sathyapalan

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