The Relationship Between Clinical Imaging and Neurobehavioral Assessment in Posthemorrhagic Ventricular Dilation of Prematurity

Frontiers in Physiology
Rebecca A DornerVera Joanna Burton

Abstract

Introduction: Neonatal intraventricular hemorrhage (IVH) and subsequent posthemorrhagic ventricular dilation and hydrocephalus of prematurity are associated with brain injury and neurodevelopmental impairment in the preterm population. Neuroimaging assesses cerebral injury and guides neurosurgical intervention; however, the relationship of head ultrasound (HUS) and magnetic resonance imaging (MRI) parameters to neonatal exams in this group has not been well described. The NICU Network Neurobehavioral Scale (NNNS) is a reproducible, highly reliable battery with motor and cognitive domain scores. Objective: To evaluate the relationship between neonatal neurobehavioral findings on the NNNS and measures of ventricular dilation and associated brain injury on HUS and MRI. Materials and Methods: Neonates with IVH and ventricular dilatation with and without posthemorrhagic hydrocephalus were enrolled. NNNS exams were performed at approximately term age equivalent. HUS indices were measured on the last HUS before initial neurosurgical procedure or that with worst ventriculomegaly if no intervention. The posterior fossa was assessed with MRI at term. Descriptive statistics including medians, interquartile ranges, means, and percentages w...Continue Reading

References

Jun 13, 2001·American Journal of Respiratory and Critical Care Medicine·A H Jobe, E Bancalari
Mar 6, 2004·Seminars in Neonatology : SN·Jane S Lee, Richard A Polin
Dec 17, 2005·Pediatric Physical Therapy : the Official Publication of the Section on Pediatrics of the American Physical Therapy Association·Marla C Mahoney, Meryl I Cohen
Apr 21, 2006·The Cochrane Database of Systematic Reviews·A Symington, J Pinelli
Dec 7, 2007·Brain : a Journal of Neurology·Chiara NosartiRobin M Murray
Apr 17, 2010·Acta Paediatrica·Margaretha J BrouwerManon J N L Benders
Nov 3, 2010·Developmental Medicine and Child Neurology·Jonna MaunuUNKNOWN PIPARI Study Group
Jan 25, 2011·Seminars in Perinatology·Barry M LesterJames F Padbury
Jun 29, 2011·Developmental Medicine and Child Neurology·Sandra FucileChantal Lau
Jul 16, 2011·Journal of Perinatology : Official Journal of the California Perinatal Association·M El-DibH Aly
Nov 16, 2011·Radiology·Margaretha J BrouwerManon J N L Benders
Dec 7, 2011·Developmental Medicine and Child Neurology·Yolande Noble, Roslyn Boyd
Jul 21, 2012·Journal of Perinatology : Official Journal of the California Perinatal Association·R F GoldsteinUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
Apr 27, 2013·AJNR. American Journal of Neuroradiology·H KidokoroT E Inder
Nov 28, 2013·Developmental Medicine and Child Neurology·Andrea GuzzettaAda Bancale
Dec 3, 2013·Seminars in Fetal & Neonatal Medicine·Alicia Jane Spittle, Jane Orton
Feb 22, 2014·Journal of Perinatology : Official Journal of the California Perinatal Association·A J TsaiK A Kennedy
Aug 8, 2015·Early Human Development·An N MassaroCatherine Limperopoulos
Mar 18, 2016·Early Human Development·Janyte C HolwerdaArend F Bos
Mar 24, 2016·Paediatric and Perinatal Epidemiology·Allison A AppletonCarmen J Marsit
Jan 26, 2018·Neurology·Lara M LeijserLinda S de Vries
Feb 15, 2018·Archives of Disease in Childhood. Fetal and Neonatal Edition·Linda S de VriesUNKNOWN ELVIS study group
Sep 1, 2018·Journal of Perinatology : Official Journal of the California Perinatal Association·Rebecca A DornerBruno P Soares

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Citations

Mar 28, 2020·Child Neurology Open·Melisa CarrascoUNKNOWN Johns Hopkins Neurosciences Intensive Care Nursery
May 16, 2020·Early Human Development·Eleanor KennedyUNKNOWN MagNUM Study Group

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Methods Mentioned

BETA
PMA

Software Mentioned

HUS
R Core Development
R

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