The relationship between excessive daytime sleepiness, disability, and mortality, and implications for life expectancy

Sleep Medicine
Winda L NgAnna Peeters

Abstract

To assess the relationship between excessive daytime sleepiness (EDS), disability, mortality, and life expectancy (with and without disability) in a cohort of middle-aged American adults. The Wisconsin Longitudinal Study, a life-course study on 10,317 high school graduates from Wisconsin, was used to assess the odds ratio (OR) between EDS in 2004 for prevalent and incident disability to 2011 through multiple logistic regression, and to estimate the hazard ratio (HR) of EDS in 2004 for mortality over ten years through a Cox proportional hazard model. We estimated age and sex-specific rates for mortality and disability from US nation-wide survey data in 2004. Combining these data with age-, sex- and EDS-specific mortality rates and disability prevalence estimated from our study, we constructed Sullivan life tables for those with and without EDS. Life expectancy (total, with, and without disability) from age 60 was estimated for those with and without EDS. The study participants were on average 64 years old and 47% were men. Those with EDS were more likely to develop disability than those without (OR 1.40, 95%CI 1.01-1.95). The HR for mortality associated with having EDS was 1.43 (95%CI 1.11-1.85). The results from life table anal...Continue Reading

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Citations

May 16, 2020·Journal of Sleep Research·Mathieu BergerRaphael Heinzer
May 7, 2020·Journal of Patient-reported Outcomes·Sha LiMary Sau Man Ip
Jul 24, 2021·Parkinsonism & Related Disorders·Jing YangHuifang Shang
Sep 23, 2021·Journal of Internal Medicine·Torbjörn Åkerstedt, Peter M Nilsson

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