PMID: 9526969Apr 4, 1998Paper

The relationship between fat distribution and coronary risk factors in sedentary postmenopausal women on and off hormone replacement therapy

Obesity Research
A C PerryP C Miller

Abstract

The purpose of this study was to examine the relationship between fat distribution and coronary risk factors (CRF) in sedentary overweight postmenopausal women both on and off hormone replacement therapy (HRT). Medical records and information were abstracted from nonsmoking women entering a weight loss program. A total of 33 women on HRT (mean age=50.12+/-5.2) and 51 nonusers (mean age=52.52+/-7.8) fulfilled subject eligibility requirements and were included in the data analysis. Results showed a significantly lower waist-to-hip ratio (WHR) (p=0.009) and waist (p=0.010) and greater levels of high-density lipoprotein cholesterol (HDL-C) (p=0.035) in HRT users than in nonusers. After converting correlations to standard Z-scores and performing z-tests, the correlation between total cholesterol (T-Chol) and WHR was significantly greater in nonusers than in HRT users (p=0.038). A multiple regression analysis showed differences between groups in the ability of age and anthropometric variables to predict CRF. Although T-Chol could be predicted in nonusers (r2=0.24; p=0.011), very low-density lipoprotein cholesterol (VLDL-C) and systolic blood pressure (SBP) could be significantly predicted in HRT users only (r2=0.28, p=0.055 and r2=0....Continue Reading

References

Aug 1, 1978·Annals of Internal Medicine·T GordonP M McNamara
Dec 1, 1976·Clinical Obstetrics and Gynecology·H L Judd
May 1, 1992·The American Journal of Clinical Nutrition·C J LeyJ C Stevenson
Sep 12, 1991·The New England Journal of Medicine·M J StampferC H Hennekens
Aug 11, 1991·American Journal of Obstetrics and Gynecology·R D Gambrell, A Z Teran
Sep 15, 1991·Annals of Internal Medicine·E Barrett-Connor
Dec 1, 1991·Metabolism: Clinical and Experimental·J HaarboC Christiansen
Jan 1, 1991·Circulation·K M AndersonW B Kannel
Jul 1, 1990·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·J P DesprésC Bouchard
Mar 29, 1990·The New England Journal of Medicine·J E MansonC H Hennekens
Sep 7, 1989·The New England Journal of Medicine·K A MatthewsR R Wing
Aug 1, 1988·American Journal of Obstetrics and Gynecology·B E HendersonR K Ross
Jun 26, 1986·The New England Journal of Medicine·B L Riggs, L J Melton
Jan 1, 1987·Annual Review of Public Health·K E PowellJ S Kendrick
Sep 1, 1986·Metabolism: Clinical and Experimental·M Rebuffé-ScriveP Björntorp
Oct 1, 1973·European Journal of Pharmacology·E AnggårdG Sedvall
Dec 1, 1994·The American Journal of Clinical Nutrition·Q WangC Christiansen
Aug 1, 1993·Journal of the American College of Cardiology·E D Frohlich
Jan 27, 1993·JAMA : the Journal of the American Medical Association·A R FolsomR J Prineas
Apr 1, 1993·Diabetes·H J Dowling, F X Pi-Sunyer
Apr 15, 1993·The New England Journal of Medicine·K A Martin, M W Freeman
Mar 1, 1996·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·C BjörkelundC Bengtsson

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Citations

Aug 15, 2003·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·T OkuraH Shimokata
Nov 13, 2014·Hormone Molecular Biology and Clinical Investigation·Arlette C Perry, Lorena Martin
Apr 9, 2008·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Susan J Whitmire

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