PMID: 1209185Jan 1, 1975Paper

The relationship between hepatitis B antigen, e-antigen, and liver-pathology in patients treated with dialysis

Scandinavian Journal of Urology and Nephrology
E NordenfeltH Henrikson

Abstract

The relationship between hepatitis B antigen (HB Ag), e-antigen and liver pathology was studied in 27 patients who had died after regular dialysis treatment. The examination of the liver histology was done without knowledge of the history of the patient. Seventeen of the patients were HB Ag positive at death and had been carriers of the antigen for between 1 and 57 months. Two had chronic aggressive hepatitis and 10 chronic persistent hepatitis, but 5 had no histological signs of chronic hepatitis. e-antigen could be found in blood samples from all these patients. The cause of kidney disease, duration of dialysis and time of carriership of HB Ag showed the same variation among the patients without as among the patients with signs of chronic hepatitis. Two patients who had been HB Ag positive but were negative at death had no signs of chronic hepatitis. HB Ag positive samples available from one of these patients were also positive for e-antigen. Eight patients who were constantly negative for HB Ag were also negative for e-antigen. One of them had autopsy findings of a chronic persistent hepatitis. There were thus very moderate or even no histological signs of chronic hepatitis among these patients in spite of prolonged carriers...Continue Reading

References

Jan 1, 1973·Scandinavian Journal of Infectious Diseases·E Nordenfelt, G Le Bouvier
Sep 11, 1969·The New England Journal of Medicine·W T LondonB S Blumberg
Jan 3, 1970·Lancet·M A CalderM E Schonell
May 11, 1970·JAMA : the Journal of the American Medical Association·S Krugman, J P Giles
Nov 1, 1973·Journal of Virology·P M KaplanW S Robinson
Dec 1, 1970·Scandinavian Journal of Infectious Diseases·E Nordenfelt, E Dahlquist

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Citations

Oct 1, 1977·Journal of Clinical Pathology·P E Gibson, K Ruparella
Aug 1, 1977·Journal of Clinical Pathology·P E Gibson
Jan 1, 1976·Scandinavian Journal of Infectious Diseases·B LöfgrenE Nordenfelt
Mar 1, 1981·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A Al-TuwaijriN R Di Luzio
Jan 1, 1982·Scandinavian Journal of Infectious Diseases·B LöfgrenB Lindergård

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