The relationship between human placental morphometry and ultrasonic measurements of utero-placental blood flow and fetal growth

Placenta
N SalavatiGordon C S Smith

Abstract

Ultrasonic fetal biometry and arterial Doppler flow velocimetry are widely used to assess the risk of pregnancy complications. There is an extensive literature on the relationship between pregnancy outcomes and the size and shape of the placenta. However, ultrasonic fetal biometry and arterial Doppler flow velocimetry have not previously been studied in relation to postnatal placental morphometry in detail. We conducted a prospective cohort study of nulliparous women in The Rosie Hospital, Cambridge (UK). We studied a group of 2120 women who had complete data on uterine and umbilical Doppler velocimetry and fetal biometry at 20, 28 and 36 weeks' gestational age, digital images of the placenta available, and delivered a liveborn infant at term. Associations were expressed as the difference in the standard deviation (SD) score of the gestational age adjusted ultrasound measurement (z-score) comparing the lowest and highest decile of the given placental morphometric measurement. The lowest decile of placental surface area was associated with 0.87 SD higher uterine artery Doppler mean pulsatility index (PI) at 20 weeks (95% CI: 0.68 to 1.07, P < 0.001). The lowest decile of placental weight was associated with 0.73 SD higher umbili...Continue Reading

Associated Clinical Trials

References

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Citations

Sep 9, 2016·Physiological Reviews·Graham J BurtonKent L Thornburg
May 1, 2020·PloS One·Helena Lucia Barroso Dos ReisAngélica Espinosa Miranda
Mar 7, 2019·Biomechanics and Modeling in Mechanobiology·Jason CarsonRaoul Van Loon
Feb 6, 2017·The Journal of Obstetrics and Gynaecology Research·Mehdi KehilaMohamed Badis Chanoufi
Nov 16, 2016·Reproduction : the Official Journal of the Society for the Study of Fertility·E MourierP Chavatte-Palmer
Jan 24, 2019·Frontiers in Physiology·Nastaran SalavatiSanne J Gordijn
Jan 28, 2019·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Mária JakóGyörgy Bártfai

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