PMID: 9187548Jan 1, 1996Paper

The relationship between portal venous and hepatic arterial blood flow. I. Experimental liver transplantation

HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery
F JakabJ Faller

Abstract

The relationship between the changes in portal venous and hepatic arterial blood flows, in the liver is a much disputed question, it has tremendous significance in the practice of transplantation, and an explanation has been available since 1981, when Lautt published the so-called "adenosine washout theory". According to our earlier observations the decrease of portal pressure or flow consistently led to an increase in hepatic artery flow. At the same time changes in hepatic artery flow or pressure seemed to produce only inconsistent effects on the portal circulation. In the present experiments liver transplantation (OLTX) was carried out on mongrel dogs by Starzl's method. Electromagnetic flow probes were placed on the hepatic artery and the portal vein before removal of recipient's liver, and after completion of all vascular anastomoses to the newly inserted liver, during the recirculatory phase of OLTX. The flow probes were connected to a Hellige electromagnetic flowmeter, portal venous and systemic arterial pressures were also recorded. The control HAF was 241 +/- 23 ml/min, the average PVF was 517 +/- 47 ml/min before removal of the recipient's liver. In the recirculatory phase of HAF increased, by 71 +/- 12% (p < 0.001). ...Continue Reading

Citations

Oct 3, 2008·Cardiovascular and Interventional Radiology·Boris RadeleffGoetz Martin Richter
Sep 18, 2002·Radiographics : a Review Publication of the Radiological Society of North America, Inc·David C MadoffSanjay Gupta
Dec 29, 2015·Transplantation Proceedings·D-Y LiuJ-X Li
Feb 26, 2010·Transplant International : Official Journal of the European Society for Organ Transplantation·Martina T MoglOlaf Guckelberger
Dec 3, 2014·The Journal of Surgical Research·Kassiani TheodorakiGeorgia Kostopanagiotou
Sep 22, 2001·Clinics in Liver Disease·N Garcia, A J Sanyal

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